The first reported use of autologous blood pleurodesis for treatment of prolonged air leak in COVID-19-related spontaneous pneumomediastinum and pneumothorax: A case report.

The first reported use of autologous blood pleurodesis for treatment of prolonged air leak in COVID-19-related spontaneous pneumomediastinum and pneumothorax: A case report.
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DOI:
10.1002/rcr2.840
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发表时间:
2021-10
影响因子:
0.8
通讯作者:
S Rashid Ali MR
S Rashid Ali MR
中科院分区:
其他
文献类型:
--
作者:
S Rashid Ali MR

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自发性纵隔气肿(SPM)和气胸(PTX)被认为是COVID - 19肺炎的罕见并发症。我们报告了一例COVID - 19肺炎患者,入院第13天并发SPM, 2天后进展为自发性PTX,需要肋间胸腔引流。在接下来的9天里,尽管继续进行低剂量吸入并插入另一个更大口径的肋间引流管,但仍出现了长时间的空气泄漏(PAL)。考虑到在COVID - 19中预期的麻醉和手术风险,手术胸膜切除术不是一种选择。鉴于此,我们选择自体血胸膜穿刺术(ABP)治疗肺泡胸膜渗漏。ABP先前已用于非COVID - 19相关的难治性自发性PTX的PAL病例。随着肺再扩张,漏气停止,临床和放射学改善良好。PTX消退后患者出院,术后需肋间引流共15天。本病例描述了首次报道的使用自体血液胸膜切除术治疗COVID - 19肺炎合并自发性纵隔气肿和气胸的长期漏气病例。
Spontaneous pneumomediastinum (SPM) and pneumothorax (PTX) have been described as rare complications of COVID‐19 pneumonia. We present a case of COVID‐19 pneumonia which was complicated by SPM on Day 13 of admission with progression to spontaneous PTX 2 days later which necessitated intercostal chest drainage. It was complicated by prolonged air leak (PAL) for the next 9 days despite being on continued low‐dose suction and another additional larger bore intercostal drain inserted. Surgical pleurodesis was not an option in view of anaesthesia and operative risk expected in COVID‐19. In view of this, autologous blood pleurodesis (ABP) to address the alveolar pleural leak was opted. ABP has been previously used for PAL in cases of non‐COVID‐19‐related intractable spontaneous PTX. The air leak ceased with subsequent lung re‐expansion, with good clinical and radiological improvement. He was discharged well after resolution of PTX which required intercostal drain for a total of 15 days. This case describes the first reported use of autologous blood pleurodesis to treat prolonged air leak in a case of COVID‐19 pneumonia which was complicated by spontaneous pneumomediastinum and pneumothorax.
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