The redoxome: Proteomic analysis of cellular redox networks.
The redoxome: Proteomic analysis of cellular redox networks.
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DOI:
10.1016/j.cbpa.2010.11.013
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发表时间:
2011-02
影响因子:
7.8
通讯作者:
Jakob U
中科院分区:
文献类型:
--
作者:
Thamsen M;Jakob U
Redox-regulated proteins play fundamentally important roles not only during the defense of organisms against oxidative stress conditions but also as targets of cellular signaling events. This realization has spurred the development of proteomic techniques geared towards characterizing the redoxome; proteins with highly reactive cysteine residues, whose thiol oxidation state controls the function of the proteins, and by extension, the pathways they are part of. We will here summarize the most recent advances made in the field of redox proteomic analyses, aimed to elucidate the cellular redox networks that appear to control pro- and eukaryotic organisms.
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影响因子:
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