Proanthocyanidin encapsulation for sustained bioactivity in dentin bioadhesion: A two-year study.
Proanthocyanidin encapsulation for sustained bioactivity in dentin bioadhesion: A two-year study.
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DOI：
10.1016/j.dental.2021.12.024
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发表时间：
2022-03
期刊：
影响因子：
--
通讯作者：
Bedran-Russo AK
中科院分区：
文献类型：
--
作者：
Alania Y;Yourdkhani M;Trevelin L;Bim-Junior O;Majithia H;Farsi L;Bedran-Russo AK
To determine the long-term effect on the stability of dentin-resin interfaces after the addition of polylactide (PLA) capsules containing proanthocyanidin (PAC) to adhesive resin. Sub-micron (SM) and micron (M) size capsules containing PACs were produced using a combination of emulsification and solvent evaporation techniques and characterized. Human dentin surfaces (n = 8) were etched (35% glycolic acid) and primed (15% enriched Vitis vinifera extract solution), followed by the application of an experimental adhesive containing 0 (control), 1.5 wt% of SM or M PAC-filled PLA capsules light cured for 40 s. A crown was built using commercial composite. After 24 h-immersion (37°C) in simulated body fluid, specimens were serially sectioned into resin-dentin beams. Microtensile bond strength (TBS), micro-permeability and fracture pattern were assessed immediately and after 1 and 2 years. Data were statistically analyzed using two-way ANOVA and post-hoc test (α = 0.05). Polydisperse capsules were manufactured with average diameter of 0.36 μm and 1.08 μm for SM and M, respectively. The addition of capsules did not affect TBS (p = 0.889). After 2 years, TBS significantly decreased in SM (p = 0.006), whereas M showed similar initial values (p = 0.291). Overall, less micro-permeability was found in M than the control and SM group (p < 0.001). After 2 years, fractured surfaces from capsule-containing groups failed within the adhesive layer while control fractured at the bottom of the hybrid layer. The addition of PAC-filled PLA microcapsules in a dental adhesive did not affect the bond strength while increased and sustained the protection against micro-permeability in the interface, likely due to release of PACs.
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影响因子：
5
作者：
Bedran-Russo, Ana K.;Pauli, Guido F.;Chen, Shao-Nong;McAlpine, James;Castellan, Carina S.;Phansalkar, Rasika S.;Aguiar, Thaiane R.;Vidal, Cristina M. P.;Napotilano, Jose G.;Nam, Joo-Won;Leme, Ariene A.
通讯作者：
Leme, Ariene A.
影响因子：
7.6
作者：
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通讯作者：
Tay, F. R.
影响因子：
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作者：
Ashraf MA;Peng W;Zare Y;Rhee KY
通讯作者：
Rhee KY
影响因子：
2.9
作者：
Ahmed, Jasim;Varshney, Sunil K.
通讯作者：
Varshney, Sunil K.
影响因子：
5
作者：
Alania, Yvette;Chiari, Marina D. S.;Braga, Roberto R.
通讯作者：
Braga, Roberto R.