The association between conception history and subsequent postpartum depression and/or anxiety: Evidence from the Clinical Practice Research Datalink 1991-2013.
The association between conception history and subsequent postpartum depression and/or anxiety: Evidence from the Clinical Practice Research Datalink 1991-2013.
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受孕史与随后的产后抑郁和/或焦虑之间的关联：来自 1991-2013 年临床实践研究数据链的证据。
DOI：
10.1016/j.jad.2022.04.138
复制
发表时间：
2022
影响因子：
6.6
通讯作者：
Tianyi FL
中科院分区：
文献类型：
--
作者：
Tianyi FL
背景不孕不育和生育治疗与心理困扰有关，这些心理困扰可能会影响随后的心理健康，包括产后抑郁和焦虑。方法从临床实践研究数据链接获得1991至2013年间生育的妇女的数据。第一胎出生前的受孕史被归类为“无生育问题”、“未经治疗的不孕症”、排卵诱导(OI)和辅助生殖技术(ART)。产后12个 月的抑郁和/或焦虑通过诊断、症状和处方记录来确定。结果在235,127名母亲中，31,947人(13.6%)有产后抑郁和/或焦虑的证据。抗逆转录病毒治疗组的母亲患产后抑郁和/或焦虑的几率比生育组的母亲低22%(OR0.78；95%CI[0.70-0.86]；p <； 0.0001)。考虑到既往的心理健康、生活方式、社会人口和怀孕相关因素，这种关联的强度降低(AOR0.87；95%CI[0.78-0.97]；p = 0.01)。在未治疗的不孕症或OI组中没有观察到显著的相关性。限制在任何常规数据分析中，记录的质量是重要的，但一些信息是不可获得的(例如，教育、社会支持)。结论与没有生育问题的妇女相比，有不孕症、OI或ART治疗的妇女产后抑郁和/或焦虑的风险不会增加。重要的是要探索，接受抗逆转录病毒治疗的女性是否不太可能经历抑郁/焦虑，或者在需要帮助时不寻求帮助，这对她们的健康和护理有影响。
BackgroundInfertility, and fertility treatment, are associated with psychological distress that may influence subsequent mental health including postpartum depression and anxiety.MethodsData for women who had a livebirth between 1991 and 2013 were drawn from the Clinical Practice Research Datalink. Conception history prior to their first recorded birth was categorised as ‘no fertility problems’, ‘untreated subfertility’, ovulation induction (OI), and assisted reproductive technologies (ART). Depression and/or anxiety in the 12 months postpartum were identified using records of diagnoses, symptoms, and prescriptions. Prevalence was compared, and odds ratios estimated using multivariable logistic regression.ResultsOf 235,127 mothers, 31,947 (13.6%) had evidence of postpartum depression and/or anxiety. Mothers in the ART group had 22% lower odds of postnatal depression and/or anxiety compared to mothers in the fertile group (OR 0.78; 95% CI [0.70–0.86]; p < 0.0001). Accounting for prior mental health, lifestyle, sociodemographic and pregnancy-related factors reduced the strength of the association (aOR 0.87; 95% CI [0.78–0.97]; p = 0.01). There were no significant associations observed in the untreated subfertility or OI groups.LimitationsAs in any analysis of routine data, the quality of recording is important and some information was unavailable (e.g. education, social support).ConclusionsWomen with a history of subfertility, OI or ART treatment were not at increased risk of postpartum depression and/or anxiety compared to those with no fertility problems. It is important to explore whether women who underwent ART are less likely to experience depression/anxiety or do not seek help when needed, with implications for their health and care.
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产后抑郁症：危险因素和干预措施的文献综述
DOI：
--
发表时间：
2003
期刊：
影响因子：
--
作者：
D. Stewart;E. Robertson;C. Dennis;S. Grace
通讯作者：
S. Grace
影响因子：
6.7
作者：
An, Yuan;Wang, Zhuoran;Wu, Kun
通讯作者：
Wu, Kun
影响因子：
6.7
作者：
Hjelmstedt, A;Widström, AM;Collins, A
通讯作者：
Collins, A
影响因子：
6.7
作者：
Lynch, Courtney D.;Prasad, Mona R.
通讯作者：
Prasad, Mona R.