Investigation of the effect of directional (off-axis) illumination on the reflectivity of retina layers in mice using swept-source optical coherence tomography
Investigation of the effect of directional (off-axis) illumination on the reflectivity of retina layers in mice using swept-source optical coherence tomography
复制标题
使用扫源光学相干断层扫描研究定向(离轴)照明对小鼠视网膜层反射率的影响
DOI:
10.1117/12.2288739
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
Manns, Fabrice
中科院分区:
文献类型:
--
作者:
Meleppat, Ratheesh K.;Zhang, Pengfei;Wahl, Daniel J.;Jian, Yifan;Manna, Suman K.;Sarunic, Marinko V.;Pugh, Edward N.;Zawadzki, Robert J.;Ju, Myeong Jin;Manns, Fabrice
Changes in visibility of the Henle fiber layer and photoreceptor bands of the human retina with illumination directionality have been reported in OCT clinical imaging. These are a direct consequence of the changes in back scattering due to fibrous tissue orientation and to waveguiding properties of the photoreceptors respectively. Here we report the preliminary results of a study on the effects of retinal images acquired with OCT of illumination directionality in the mouse retina. The quantitative assessment of the reflectivity of retinal layers of a BALB/c and WT pigmented mice was performed in-vivo using a swept-source optical coherence tomography system. The intensities of backscattered signals from different outer retinal layers were measured and compared.
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