Approach to a positive urine culture in a patient without urinary symptoms.

Approach to a positive urine culture in a patient without urinary symptoms.
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DOI:
10.1016/j.idc.2013.09.005
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发表时间:
2014-03
影响因子:
4.4
通讯作者:
Grigoryan L
Grigoryan L
中科院分区:
医学3区
文献类型:
--
作者:
Trautner BW;Grigoryan L

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无症状菌尿(ASB)是一种疾病,其中细菌存在于从患者收集的未污染的尿液样本中,而没有与尿路相关的体征或症状。ASB必须通过缺乏与UTI相符的体征和症状或通过临床确定非泌尿病因解释患者的症状来与症状性UTI区分。ABU是一种非常常见的疾病,通常不必要地使用抗生素治疗。孕妇和接受泌尿外科手术的人预计会导致粘膜出血,这是仅有的两组有令人信服的证据表明筛查和治疗ASB是有益的。ASB筛查和/或治疗的随机对照试验已确定在绝经前成年女性、糖尿病女性、脊髓损伤患者、导管插入患者、社区老年人和老年机构化成人中缺乏疗效。本综述的总体目的是提高人们对ASB与UTI不同的认识,并使临床医生能够在不适用抗菌治疗菌尿的情况下保留抗生素。
Asymptomatic bacteriuria (ASB) is a condition in which bacteria are present in a noncontaminated urine sample collected from a patient without signs or symptoms related to the urinary tract. ASB must be distinguished from symptomatic UTI by the absence of signs and symptoms compatible with UTI or by clinical determination that a nonurinary etiology accounts for the patient's symptoms. ABU is a very common condition that is often treated unnecessarily with antibiotics. Pregnant women and persons undergoing urologic procedures expected to cause mucosal bleeding are the only two groups with convincing evidence that screening for and treating ASB is beneficial. Randomized, controlled trials of ASB screening and/or treatment have established the lack of efficacy in premenopausal adult women, diabetic women, patients with spinal cord injury, catheterized patients, older adults living in the community, and elderly institutionalized adults. The overall purpose of this review is to promote an awareness of ASB as a distinct condition from UTI and to empower clinicians to withhold antibiotics in situations in which antimicrobial treatment of bacteriuria is not indicated.
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