ICTV Virus Taxonomy Profile: Herpesviridae 2021.

ICTV Virus Taxonomy Profile: Herpesviridae 2021.
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DOI:
10.1099/jgv.0.001673
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发表时间:
2021-10
期刊:
The Journal of general virology
影响因子:
--
通讯作者:
Davison AJ
Davison AJ
中科院分区:
其他
文献类型:
--
作者:
Gatherer D;Depledge DP;Hartley CA;Szpara ML;Vaz PK;Benkő M;Brandt CR;Bryant NA;Dastjerdi A;Doszpoly A;Gompels UA;Inoue N;Jarosinski KW;Kaul R;Lacoste V;Norberg P;Origgi FC;Orton RJ;Pellett PE;Schmid DS;Spatz SJ;Stewart JP;Trimpert J;Waltzek TB;Davison AJ

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疱疹病毒科的成员具有包膜的球形病毒体,其具有由对称和非对称组分组成的特征性复杂结构。125-241 kbp的线性双链DNA基因组包含70-170个基因,其中43个基因遗传自祖先疱疹病毒。一般来说,疱疹病毒与其宿主共同进化并高度适应,这些宿主包括许多哺乳动物、鸟类和爬行动物物种。在初次感染后,它们能够建立终身潜伏感染,在此期间病毒基因表达有限。严重的疾病通常只在胎儿、幼儿、免疫功能低下或感染替代宿主后观察到。这是国际病毒分类委员会(ICTV)关于疱疹病毒科的报告摘要,可在ictv.global/report/herpesviridae上查阅。
Members of the family Herpesviridae have enveloped, spherical virions with characteristic complex structures consisting of symmetrical and non-symmetrical components. The linear, double-stranded DNA genomes of 125–241 kbp contain 70–170 genes, of which 43 have been inherited from an ancestral herpesvirus. In general, herpesviruses have coevolved with and are highly adapted to their hosts, which comprise many mammalian, avian and reptilian species. Following primary infection, they are able to establish lifelong latent infection, during which there is limited viral gene expression. Severe disease is usually observed only in the foetus, the very young, the immunocompromised or following infection of an alternative host. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Herpesviridae, which is available at ictv.global/report/herpesviridae.
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发表时间: 2003-11-21
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