The in vitro effects of chlorhexidine on subgingival plaque bacteria.

The in vitro effects of chlorhexidine on subgingival plaque bacteria.
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氯己定对龈下菌斑细菌的体外影响。

DOI:
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发表时间:
1989
影响因子:
6.7
通讯作者:
H. Newman
H. Newman
中科院分区:
医学1区
文献类型:
--
作者:
A. Stanley;M. Wilson;H. Newman

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本研究的目的是确定从龈下菌斑中分离出的一系列细菌对洗必泰的敏感性。此外,还观察了洗必泰对慢性炎症性牙周病患者龈下菌斑中细菌存活的影响。洗必泰对52株细菌的最低抑菌浓度为8~500微克/毫升,最低抑菌浓度为62微克/毫升,%的受试菌在该浓度下有抑制作用。浓度为250微克/毫升的洗必泰对所调查的25个牙菌斑样本中的所有细菌均有抑制作用。样品对洗必泰的最低抑菌浓度为31~250微克/毫升,模式值为125微克/毫升。
The purpose of this study was to determine the susceptibility to chlorhexidine of a range of bacteria which may be isolated from subgingival plaque. In addition, the effect of chlorhexidine on the survival of bacteria in subgingival plaque samples from patients with chronic inflammatory periodontal disease was investigated. The minimum inhibitory concentration (MIC) of chlorhexidine for 52 strains of bacteria ranged from 8 to 500 micrograms/ml. The modal value of the MIC was found to be 62 micrograms/ml, 64% of the strains tested being inhibited at this concentration. A concentration of 250 micrograms/ml of chlorhexidine inhibited the growth of all bacteria in the 25 subgingival plaque samples investigated. The MIC of chlorhexidine for the samples ranged from 31 to 250 micrograms/ml, the modal value being 125 micrograms/ml.
龈下菌斑样本的抗生素敏感性测试。
DOI: 10.1111/j.1600-051x.1983.tb01291.x
发表时间: 1983
影响因子: 6.7
作者:
Walker,CB;Gordon,JM;Socransky,SS
通讯作者: Socransky,SS