Antibiotic practices among household members and their domestic animals within rural communities in Cumilla district, Bangladesh: a cross-sectional survey.
Antibiotic practices among household members and their domestic animals within rural communities in Cumilla district, Bangladesh: a cross-sectional survey.
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DOI：
10.1186/s12889-021-10457-w
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发表时间：
2021-02-25
影响因子：
4.5
通讯作者：
King R
中科院分区：
文献类型：
--
作者：
Hicks JP;Latham SM;Huque R;Das M;Newell J;Abdullah SM;Al Azdi Z;Jahan I;Rassi C;Hamade P;Shafique M;Islam MS;King R
抗生素耐药性是对人类健康的全球性威胁，而在人类和动物中不适当地使用抗生素被广泛认为是抗生素耐药性感染的关键驱动因素。在低收入国家，尤其是中等收入国家，抗生素在人类和动物中的使用正在迅速增长。然而，在这些国家的社区环境中，几乎没有关于在人类和动物中使用抗生素的做法的详细了解。在这里，我们旨在了解孟加拉国库米拉地区农村家庭与家庭成员及其家畜有关的抗生素做法。2018年，我们采用具有代表性的整群抽样方法进行了横断面调查。我们收集了682名女性和620名男性户主的自我报告信息，女性也被问及她们孩子的抗生素使用情况。只有48%(95%CI：40，56%)的男性和女性听说过抗生素，而在知道抗生素的女性和男性及其子女中，70%(95%CI：，76%)报告曾服用过抗生素，而在这些报告曾服用抗生素的人中，21%(95%CI：18，25%)表示最近一次使用抗生素是在最近一个月内。在人类和动物中危险/不适当的抗生素做法经常被报道。例如，在知道抗生素的女性和男性及其子女中，52%(95%可信区间：40%，63%)报告曾因“咳嗽/感冒”而服用抗生素，尽管抗生素通常不适合用于治疗病毒性上呼吸道感染。在知道抗生素的家禽养殖者中，11%(95%可信区间：8，15%)报告曾服用健康的家禽抗生素，主要用于生长/预防，而在知道抗生素并曾给牛饲料的养牛者中，20%(95%可信区间：9，37%)表示饲料中至少有时含有抗生素。我们的研究结果强调了在社区和卫生系统两个层面采取因地制宜的干预措施的必要性，以减少孟加拉国农村地区人和家畜中不适当的抗生素使用。成功地减少人和动物之间不适当地使用抗生素是解决抗菌素耐药性的必要和关键步骤。网上版载有补充材料，可在10.1186/s12889-021-10457-w查阅。
Antibiotic resistance is a global threat to human health, and inappropriate use of antibiotics in humans and animals is widely considered to be a key driver of antibiotic resistant infections. Antibiotic use in humans and animals is growing rapidly in low- and, particularly, middle-income countries. However, there is little detailed understanding about practices related to the use of antibiotics in humans and animals within community settings in such countries. Here we aimed to understand the antibiotic practices of rural households across Cumilla district, Bangladesh, in relation to household members and their domestic animals. In 2018 we conducted a cross-sectional survey using representative cluster sampling methods. We collected self-reported information from 682 female and 620 male household heads, with women also asked about their children’s antibiotic practices. Only 48% (95% CI: 40, 56%) of women and men had heard of antibiotics, and among those women and men who were aware of antibiotics and the children of those women 70% (95% CI: 64, 76%) reported having previously taken antibiotics, while among these individuals who reported previously taking antibiotics 21% (95% CI: 18, 25%) said they had done so most recently within the last month. Risky/inappropriate antibiotic practices in humans and animals were often reported. For example, among women and men who were aware of antibiotics and the children of those women 52% (95% CI: 40, 63%) reported previously taking antibiotics for a “cough/cold”, despite antibiotics being typically inappropriate for use against viral upper respiratory tract infections. Among poultry-owning respondents who were aware of antibiotics 11% (95% CI: 8, 15%) reported previously giving healthy poultry antibiotics, mainly for growth/prophylaxis, while among cattle-owning respondents who were aware of antibiotics and reported previously giving their cattle feed 20% (95% CI: 9, 37%) said the feed had contained antibiotics at least sometimes. Our results highlight the need for context-adapted interventions at both the community level and the health systems level to reduce inappropriate antibiotic use among humans and domestic animals in rural Bangladesh. Successfully reducing inappropriate use of antibiotics among humans and animals is a required and critical step in tackling antimicrobial resistance. The online version contains supplementary material available at 10.1186/s12889-021-10457-w.
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影响因子：
3.7
作者：
Ding L;Sun Q;Sun W;Du Y;Li Y;Bian X;He G;Bai H;Dyar OJ
通讯作者：
Dyar OJ
影响因子：
5.2
作者：
Dyar, Oliver J.;Yin, Jia;Lundborg, Cecilia Stalsby
通讯作者：
Lundborg, Cecilia Stalsby
影响因子：
2.6
作者：
Dyar, Oliver J.;Zhang, Tianyang;Lundborg, Cecilia Stalsby
通讯作者：
Lundborg, Cecilia Stalsby
影响因子：
1.7
作者：
Dognon, S. R.;Antoine-Moussiaux, N.;Youssao, A. K. I.
通讯作者：
Youssao, A. K. I.
影响因子：
3.9
作者：
Bianco, Aida;Papadopoli, Rosa;Pavia, Maria
通讯作者：
Pavia, Maria