Acetylcholinesterase-catalyzed hydrolysis allows ultrasensitive detection of pathogens with the naked eye.
Acetylcholinesterase-catalyzed hydrolysis allows ultrasensitive detection of pathogens with the naked eye.
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乙酰胆碱酯酶催化的水解允许用肉眼超灵敏地检测病原体。
DOI:
10.1002/anie.201307952
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发表时间:
2013-12-23
影响因子:
16.6
通讯作者:
Chen, Xiaoyuan
中科院分区:
文献类型:
--
作者:
Liu, Dingbin;Wang, Zhantong;Jin, Albert;Huang, Xinglu;Sun, Xiaolian;Wang, Fu;Yan, Qiang;Ge, Shengxiang;Xia, Ningshao;Niu, Gang;Liu, Gang;Walker, A. R. Hight;Chen, Xiaoyuan
This paper describes a rapid diagnostic platform for pathogen detection based on the acetylcholinesterase-catalyzed hydrolysis reaction. Owing to the signal amplification strategies, the sensitivity of this assay is comparable to that of PCR. In addition, the readout of this assay is based on the color change of solutions, which can be easily observed by the naked eye alone.
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影响因子:
5.8
作者:
ELLMAN, GL;COURTNEY, KD;FEATHERSTONE, RM
通讯作者:
FEATHERSTONE, RM
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通讯作者:
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