The effect of hybridization of Culex pipiens complex mosquitoes on transmission of West Nile virus.
The effect of hybridization of Culex pipiens complex mosquitoes on transmission of West Nile virus.
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DOI：
10.1186/1756-3305-6-305
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发表时间：
2013-10-23
影响因子：
3.2
通讯作者：
Kramer LD
中科院分区：
文献类型：
--
作者：
Ciota AT;Chin PA;Kramer LD
复杂的库蚊分布在全球，是具有公共卫生意义的病原体的主要媒介。在美国，Cx。[j]；pipiens由pipiens和Cx组成。库蚊属，以及Cx属。致倦库蚊是西尼罗病毒（WNV；黄病毒科，黄病毒）的主要媒介。这些蚊子居住在不同但重叠的生态位中，并且很容易在它们共存的地区杂交。虽然已经确定了库蚊传播西尼罗河病毒的媒介能力的物种和种群特异性差异，但尚未很好地表征该复合体内杂交在多大程度上改变了西尼罗河病毒的传播潜力。Cx实验室菌落西尼罗河病毒载体能力的研究。p. f. pipiens, c .；p. f. molestus，和Cx。对致倦库蚊进行了评估，并与这些系的互交产生的杂交种群进行了比较。结果表明，杂交对西尼罗河病毒在库蚊复合体中的感染、传播，尤其是传播有显著影响。具体来说，在所有杂交群体中，相对于一个或两个亲本菌株，西尼罗河病毒的传播增强了。这些结果表明，环境或人为变化导致库蚊杂交种群分布和范围的波动可能对西尼罗河病毒在自然界的传播模式产生重大影响。
Culex pipiens L. complex mosquitoes have a global distribution and are primary vectors of pathogens of public health significance. In the U.S., Cx. pipiens bioformes, Cx. pipiens form pipiens and Cx. pipiens form molestus, as well as Cx. quinquefasciatus, are primary vectors of West Nile virus (WNV; Flaviviridae, Flavivirus). These mosquitoes reside in distinct but overlapping ecological niches and readily hybridize in areas where they coexist. Although species and population-specific differences in vector competence of Culex mosquitoes for WNV have been identified, the extent to which hybridization within this complex alters WNV transmission potential has not been well characterized. WNV vector competence of laboratory colonies of Cx. p. f. pipiens, Cx. p. f. molestus, and Cx. quinquefasciatus was assessed and compared to hybrid populations created from reciprocal mating of these lines. The results demonstrate that hybridization has a significant effect on WNV infection, dissemination, and, particularly, transmission in Culex pipiens L. complex mosquitoes. Specifically, enhanced transmission of WNV was measured in all hybrid populations relative to one or both parental stains. These findings demonstrate that environmental or anthropogenic changes resulting in fluctuations in the distribution and extent of hybrid populations of Culex mosquitoes could have a significant impact on transmission patterns of WNV in nature.
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影响因子：
56.9
作者：
Fonseca, DM;Keyghobadi, N;Wilkerson, RC
通讯作者：
Wilkerson, RC
DOI：
10.2987/8756-971x-28.4s.137
发表时间：
2012-12-01
影响因子：
1
作者：
Andreadis, Theodore G.
通讯作者：
Andreadis, Theodore G.
影响因子：
2.1
作者：
Dasgupta, Ranjit;Free, Heather M.;Christensen, Bruce M.
通讯作者：
Christensen, Bruce M.
DOI：
10.2987/8756-971x-28.4.123
发表时间：
2012-12-01
影响因子：
1
作者：
Turell, Michael J.
通讯作者：
Turell, Michael J.
中国按蚊群（双翅目：蚊科）：核糖体 DNA 内转录间隔区 2 序列推断的物种区分和系统发育关系
影响因子：
2.1
作者：
Afrane, YA;Lawson, BW;Yan, GY
通讯作者：
Yan, GY