The rapid development of high speed, resolution and precision in fMRI.

The rapid development of high speed, resolution and precision in fMRI.
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DOI:
10.1016/j.neuroimage.2012.01.049
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发表时间:
2012-08-15
期刊:
影响因子:
5.7
通讯作者:
Yacoub, Essa
Yacoub, Essa
中科院分区:
医学1区
文献类型:
--
作者:
Feinberg, David A.;Yacoub, Essa

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为了提高功能磁共振成像的速度和空间分辨率而设计的MRI脉冲序列一直是研究的热点。在这里,我们回顾和记录了一些脉冲序列思想背后的历史,这些思想不仅有助于增强fMRI采集,而且有助于扩散成像。(i)偏傅立叶EPI允许延长回声序列以获得更高的空间分辨率,同时保持最佳的TE和BOLD灵敏度。(ii)内容积EPI更名为zoom -EPI,实现了极高的空间分辨率,并已应用于7特斯拉的功能磁共振成像,用于解析皮质层活动和柱状水平的功能磁共振成像。(iii)早期的非bold方法虽然在fMRI中不成功,但它创造了双极脉冲的扩散序列,称为“两次再聚焦自旋回波”,现在广泛用于高分辨率DTI和HARDI神经元纤维轨迹成像。(iv)复用EPI将TR缩短到几百毫秒,提高了fMRI的采样率和统计功率。
MRI pulse sequences designed to increase the speed and spatial resolution of fMRI have always been a hot topic. Here, we review and chronicle the history behind some of the pulse sequence ideas that have contributed not only to the enhancement of fMRI acquisition but also to diffusion imaging. (i) Partial Fourier EPI allows lengthening echo trains for higher spatial resolution while maintaining optimal TE and BOLD sensitivity. (ii) Inner-volume EPI renamed zoomed-EPI, achieves extremely high spatial resolution and has been applied to fMRI at 7 Tesla to resolve cortical layer activity and columnar level fMRI. (iii) An early non-BOLD approach while unsuccessful for fMRI created a diffusion sequence of bipolar pulses called ‘twice refocused spin echo’ now widely used for high resolution DTI and HARDI neuronal fiber track imaging. (iv) Multiplexed EPI shortens TR to a few hundred millisecond, increasing sampling rates and statistical power in fMRI.
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