Conditioned opioid activity in the rat fetus.

Conditioned opioid activity in the rat fetus.
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大鼠胎儿中的条件阿片类药物活性。

DOI:
10.1037//0735-7044.107.6.963
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发表时间:
1993
影响因子:
1.9
通讯作者:
Smotherman,WP
Smotherman,WP
中科院分区:
医学4区
文献类型:
--
作者:
Arnold,HM;Robinson,SR;Spear,NE;Smotherman,WP

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通过 4 个实验研究了大鼠胎儿(胚胎第 20 天)的经典条件反射。在口周皮肤反应性生物测定中,与无条件刺激(UCS;牛奶)配对 3 次后,再次接触 CS(蔗糖)可减少胎儿面部擦拭次数。仅在接受 CS 和 UCS 配对呈现的 S 中,反应性降低才明显,并且不能归因于习惯、对 CS 的敏感性或条件试验期间 UCS 暴露的长期影响。在 CS 再次暴露期间,胎儿关注的是蔗糖输注的化学感觉,而不是触觉。胎儿反应性的变化是由内源性阿片系统(特别是 mu 阿片受体)的条件活动引起的。这些数据证实,大鼠胎儿能够在子宫内表现出条件性阿片类药物反应。(PsycINFO 数据库记录 (c) 2016 APA,保留所有权利)
Classical conditioning in the rat fetus (Embryonic Day 20) was investigated in 4 experiments. Reexposure to a CS (sucrose), after 3 pairings with an unconditioned stimulus (UCS; milk), reduced fetal facial wiping in a bioassay of perioral cutaneous responsiveness. Reduced responsiveness was evident only in Ss that received paired presentations of the CS and UCS and cannot be attributed to habituation, sensitization to the CS, or protracted effects of UCS exposure during conditioning trials. Fetuses attended to the chemosensory, not the tactile, qualities of the sucrose infusion during CS reexposure. Changes in fetal responsiveness resulted from conditioned activity in the endogenous opioid system, specifically at mu opioid receptors. These data confirm that the rat fetus is capable of exhibiting a conditioned opioid response in utero.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
以非哺乳期哺乳作为奖励的 10 日龄大鼠的食欲学习、模式交替和灭绝
DOI: --
发表时间: 1976
期刊: Nature
影响因子: 64.8
作者:
A. Amsel;David R. Burdette;R. Letz
通讯作者: R. Letz
牛奶和人工乳头的体验促进了大鼠胎儿的条件性阿片类药物活性。
DOI: 10.1002/dev.420260702
发表时间: 1993
影响因子: 2.2
作者:
Robinson,SR;Arnold,HM;Spear,NE;Smotherman,WP
通讯作者: Smotherman,WP
DOI: 10.1126/science.7192882
发表时间: 1981-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
BRAKE, SC
通讯作者: BRAKE, SC
发展心理生物学:新方法和不断变化的概念
DOI: --
发表时间: 1991
期刊:
影响因子: --
作者:
H. Shair;G. Barr;M. Hofer
通讯作者: M. Hofer
DOI: 10.1037/h0077628
发表时间: 1979-01-01
期刊: JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子: --
作者:
HALL, WG
通讯作者: HALL, WG