Immunotherapy of house dust mite allergy.

Immunotherapy of house dust mite allergy.
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屋尘螨过敏的免疫疗法

DOI:
10.1080/21645515.2017.1364823
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发表时间:
2017-10-03
影响因子:
4.8
通讯作者:
Zhu R
Zhu R
中科院分区:
医学3区
文献类型:
--
作者:
Yang L;Zhu R

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屋尘螨(HDM)是世界范围内室内空气变应原的主要来源,可引起过敏性疾病,包括过敏性鼻结膜炎、过敏性哮喘、特应性湿疹等。过敏原特异性免疫治疗(AIT)是HDM过敏受试者唯一潜在的疾病修饰治疗。然而,由于没有普遍接受的过敏原标准化和缺乏严格的临床研究来确认安全性和有效性,AIT仍然没有得到充分利用。在变态反应领域的医生和研究人员的努力下,AIT的有效性、安全性、标准化和策略正在不断发展。本文根据近期发表的临床试验和荟萃分析,对该领域的最新研究进行综述。
House dust mite (HDM) is a predominant source of indoor aeroallergen worldwide, which induces allergic diseases including allergic rhinoconjunctivitis, allergic asthma, atopic eczema and other allergic skin diseases. Allergen specific immunotherapy (AIT) is the only potential disease-modifying treatment of HDM allergic subjects. However, AIT remains underused due to no universally accepted allergen standardization and a shortage of rigorous clinical studies to confirm safety and efficacy. With the effort of doctors and researchers in allergy field, efficacy, safety, standardization and strategy of AIT are being continuously developed. This review presents the updated research based on recently published trials and meta-analyses.
EAACI:欧洲免疫疗法宣言。设计过敏原特异性免疫疗法的未来。
DOI: 10.1186/2045-7022-2-20
发表时间: 2012-10-30
影响因子: 4.4
作者:
Calderon MA;Demoly P;Gerth van Wijk R;Bousquet J;Sheikh A;Frew A;Scadding G;Bachert C;Malling HJ;Valenta R;Bilo B;Nieto A;Akdis C;Just J;Vidal C;Varga EM;Alvarez-Cuesta E;Bohle B;Bufe A;Canonica WG;Cardona V;Dahl R;Didier A;Durham SR;Eng P;Fernandez-Rivas M;Jacobsen L;Jutel M;Kleine-Tebbe J;Klimek L;Lötvall J;Moreno C;Mosges R;Muraro A;Niggemann B;Pajno G;Passalacqua G;Pfaar O;Rak S;Senna G;Senti G;Valovirta E;van Hage M;Virchow JC;Wahn U;Papadopoulos N
通讯作者: Papadopoulos N
DOI: 10.1159/000337654
发表时间: 2012
影响因子: 2.8
作者:
Casset A;Mari A;Purohit A;Resch Y;Weghofer M;Ferrara R;Thomas WR;Alessandri C;Chen KW;de Blay F;Valenta R;Vrtala S
通讯作者: Vrtala S
DOI: 10.1183/09031936.00138606
发表时间: 2007-02-01
影响因子: 24.3
作者:
Bousquet, J.;Dahl, R.;Khaltaev, N.
通讯作者: Khaltaev, N.
DOI: 10.1016/j.jaci.2013.09.004
发表时间: 2013-12-01
影响因子: 14.2
作者:
Calderon, Moises A.;Casale, Thomas B.;Demoly, Pascal
通讯作者: Demoly, Pascal
DOI: 10.1186/s40413-015-0078-8
发表时间: 2015
期刊: The World Allergy Organization journal
影响因子: --
作者:
Bachert C;Larché M;Bonini S;Canonica GW;Kündig T;Larenas-Linnemann D;Ledford D;Neffen H;Pawankar R;Passalacqua G
通讯作者: Passalacqua G