Soccer players under regular training show oxidative stress but an improved plasma antioxidant status.
Soccer players under regular training show oxidative stress but an improved plasma antioxidant status.
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接受定期训练的足球运动员表现出氧化应激，但血浆抗氧化状态有所改善。
DOI：
10.1042/cs0960381
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发表时间：
1999
期刊：
影响因子：
6
通讯作者：
S. Llesuy
中科院分区：
文献类型：
--
作者：
F. Brites;P. Evelson;M. Christiansen;M. Nicol;M. Basílico;R. Wikinski;S. Llesuy
众所周知，体力活动会在剧烈运动的个体中诱导氧化应激。在这项研究中，我们调查了一组足球运动员从事定期训练计划的脂蛋白谱和血浆抗氧化状态。与有氧运动所预期的一样，运动员的高密度脂蛋白胆固醇（HDL-C）和HDL 3-C水平显著升高（P<0.05）。运动员血浆总抗氧化能力比对照组高25%（P<0.005）。因此，血浆水溶性抗氧化剂水平（抗坏血酸和尿酸）被发现在足球运动员中显着升高（P<0.005）。此外，与对照组相比，这些受试者的血浆中α-生育酚浓度较高（P<0.005）。此外，血浆超氧化物歧化酶活性也随运动量的增加而升高（P<0.01）。血浆中抗氧化酶活性的升高和低分子量的自由基清除剂的较高水平可以补偿由身体活动引起的氧化应激。血浆中高水平的高密度脂蛋白可以通过抑制低密度脂蛋白氧化从而抑制脂溶性抗氧化剂的消耗来提供额外的保护。因此，定期训练的足球运动员显示出改善的血浆抗氧化状态相比，久坐不动的控制。
Physical activity is known to induce oxidative stress in individuals subjected to intense exercise. In this study, we investigated the lipoprotein profile and the plasma antioxidant status in a group of soccer players engaged in a regular training programme. As was expected for aerobic exercise, high-density lipoprotein-cholesterol (HDL-C) and HDL3-C levels were significantly increased in the sportsmen (P<0.05). Total plasma antioxidant capacity was 25% higher in sportsmen than in controls (P<0.005). Accordingly, plasma hydrosoluble antioxidant levels (ascorbic acid and uric acid) were found to be significantly elevated in the soccer players (P<0.005). In addition, these subjects showed high concentrations of alpha-tocopherol in plasma compared with controls (P<0.005). Furthermore, an increase in plasma superoxide dismutase activity was also observed in relation to exercise (P<0.01). The elevation in plasma activities of antioxidant enzymes and the higher levels of free radical scavengers of low molecular mass may compensate the oxidative stress caused by physical activity. High levels of high-density lipoprotein in plasma may offer additional protection by inhibiting low-density lipoprotein oxidation and thus liposoluble antioxidant consumption. Therefore, soccer players under regular training show an improved plasma antioxidant status in comparison to sedentary controls.
DOI：
10.1073/pnas.78.11.6858
发表时间：
1981-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
AMES, BN;CATHCART, R;HOCHSTEIN, P
通讯作者：
HOCHSTEIN, P
DOI：
10.1016/0005-2760(90)90314-n
发表时间：
1990-05-22
期刊：
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子：
--
作者：
PARTHASARATHY, S;BARNETT, J;FONG, LG
通讯作者：
FONG, LG
超越胆固醇。
DOI：
10.1056/nejm198904063201407
发表时间：
1989
期刊：
The New England journal of medicine
影响因子：
--
作者：
Steinberg,D;Parthasarathy,S;Carew,TE;Khoo,JC;Witztum,JL
通讯作者：
Witztum,JL