A Model for Estimating the Blood Flow of the POLVAD Pulsatile Ventricular Assist Device
A Model for Estimating the Blood Flow of the POLVAD Pulsatile Ventricular Assist Device
复制标题
POLVAD 脉动心室辅助装置血流量估算模型
DOI：
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发表时间：
2018
影响因子：
4.6
通讯作者：
K. Janiszowski
中科院分区：
文献类型：
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作者：
A. Siewnicka;K. Janiszowski
<italic>目的</italic>：建立POLVAD-MEV脉动式心室辅助装置（VAD）的血流速度模型。适当的流速对于恢复生理心输出量至关重要。不幸的是，在临床心脏支持期间，在设备内既不能测量血流也不能测量压力。通常，流速取决于控制参数和患者状况。然而，患者的血液动力学参数并没有被持续监测。因此，应根据器械控制单元的标准测量值评价血流。<italic>方法：</italic>模型识别数据取自一个由VAD连接到混合心血管模拟器组成的研究站。这些研究是在不同的工作和控制条件下进行的。提出了一种心室辅助装置的复合模型。首先，对供应单元的空转的驱动压力波形进行建模。接下来，基于驱动压力的测量值与怠速运行的模型化值之间的差来估计血流。<italic>结果</italic>：开发的模型的质量是好的（<inline-formula><tex-math notation="LaTeX">$\overline {{\boldsymbol{R}^2}} = 0.92$</tex-math></inline-formula>）和类似的所有测试的情况下，证实了所提出的解决方案的高通用性。<italic>结论</italic>：根据器械控制单元的标准信号估计血流速度;因此，无需进行额外测量。<italic>意义</italic>：所开发的模型在VAD控制单元中的应用将有助于控制参数的选择，并可能有助于自适应控制系统的开发。这项工作的初步版本在<xref ref-type="bibr" rid="ref1">[1]</xref>中报道。
<italic>Objective</italic>: The aim of this work was to model the blood flow rate of the POLVAD-MEV pulsatile ventricular assist device (VAD). An adequate flow rate is crucial to restore physiological cardiac output. Unfortunately, during clinical heart support, neither blood flows nor pressures can be measured within the device. In general, the flow rate depends on the control parameters and patient conditions. However, the patient's hemodynamic parameters are not constantly monitored. Therefore, blood flow should be evaluated based on the standard measurements from the device control unit. <italic>Methods:</italic> The model identification data were taken from a research stand consisting of a VAD connected to a hybrid cardiovascular simulator. The studies were conducted under different work and control conditions. A compound model of a ventricular assist device was proposed. First, the driving pressure waveform for an idle run of the supply unit is modeled. Next, the blood flow is estimated based on the difference between the measured value of driving pressure and the modeled value for an idle run. <italic>Results </italic>: The quality of the developed model is good (<inline-formula><tex-math notation="LaTeX">$\overline {{\boldsymbol{R}^2}} = 0.92$</tex-math></inline-formula>) and similar for all tested cases, confirming the high versatility of the proposed solution. <italic>Conclusion</italic>: The blood flow rate is estimated based on standard signals from the device control unit; therefore, no additional measurements are necessary. <italic>Significance </italic>: The developed model application in the VAD control unit will aid the selection of control parameters and might be useful for the development of the adaptive control system. A preliminary version of this work was reported in <xref ref-type="bibr" rid="ref1">[1]</xref>.
使用左心室辅助装置对心血管系统进行数字建模。
DOI：
10.1097/00002480-199901000-00019
发表时间：
1999
期刊：
ASAIO journal (American Society for Artificial Internal Organs : 1992)
影响因子：
--
作者：
Zhou,J;Armstrong,GP;Medvedev,AL;Smith,WA;Golding,LA;Thomas,JD
通讯作者：
Thomas,JD