Faithful Artificial Chromosome Propagation Using Spermatogonial Stem Cells.
Faithful Artificial Chromosome Propagation Using Spermatogonial Stem Cells.
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DOI:
10.1016/j.tig.2017.10.003
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发表时间:
2017-12
期刊:
影响因子:
--
通讯作者:
Seandel M
中科院分区:
文献类型:
--
作者:
Yamada M;Seandel M
Artificial chromosomes are useful in making functional vectors for very large genes, studying chromosome physiology, and modeling chromosomal disorders. Shinohara et al. have succeeded for the first time in creating transchromosomic mice by manipulating spermatogonial stem cells, which exhibited superior chromosomal stability compared to embryonic stem cells.
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