Diagnosis and management of clinical chorioamnionitis.

Diagnosis and management of clinical chorioamnionitis.
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DOI:
10.1016/j.clp.2010.02.003
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发表时间:
2010-06
影响因子:
2.1
通讯作者:
Andrews WW
Andrews WW
中科院分区:
医学4区
文献类型:
--
作者:
Tita AT;Andrews WW

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绒毛膜羊膜炎是一种常见的妊娠并发症,与严重的孕产妇、围产期和长期不良结局相关。产妇不良结局包括产后感染和败血症,而婴儿不良结局包括死产、早产、新生儿败血症、慢性肺病和导致脑瘫和其他神经发育障碍的脑损伤。过去二十年的研究扩大了我们对羊膜内感染与早产之间以及早产儿和足月儿发病之间机制联系的理解。最近和正在进行的针对诊断、治疗和预防绒毛膜羊膜炎的更好方法的临床研究可能会对新生儿的短期和长期结局产生重大影响。
Chorioamnionitis is a common complication of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include postpartum infections and sepsis while adverse infant outcomes include stillbirth, premature birth, neonatal sepsis, chronic lung disease and brain injury leading to cerebral palsy and other neurodevelopmental disabilities. Research in the last two decades has expanded our understanding of the mechanistic links between intraamniotic infection and preterm delivery as well as morbidities of preterm and term infants. Recent and ongoing clinical research into better methods for diagnosing, treating and preventing chorioamnionitis is likely to have a substantial impact on short and long-term outcomes in the neonate.
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发表时间: 1993-01-01
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