Rapid neo-sex chromosome evolution and incipient speciation in a major forest pest.

Rapid neo-sex chromosome evolution and incipient speciation in a major forest pest.
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DOI:
10.1038/s41467-017-01761-4
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发表时间:
2017-11-17
影响因子:
16.6
通讯作者:
Good JM
Good JM
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Bracewell RR;Bentz BJ;Sullivan BT;Good JM

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基因组进化预计将迅速建立新的(新)性染色体,但它是不知道如果新的性染色体进化中发挥重要作用的物种。在这里,我们结合联合收割机广泛的交叉实验与人口和功能基因组数据,研究新XY染色体的进化和早期物种形成的山松甲虫。我们发现了一个广泛的连续性的内在不相容性的杂交雄性,增加了生殖隔离人群之间的地理距离的强度。生殖隔离的这种惊人进展与广泛的基因特化、自然选择和两条性染色体上的遗传分化有关。通过杂交雄性不育分离的密切相关的群体也显示出在结构和雄性特异性基因内容上不同的替代新Y单倍型的固定。我们的研究结果表明,新的性染色体进化可以驱动密切相关的人群之间的快速功能分歧,而不管生态驱动因素的分歧。新的性染色体的进化可能导致生殖隔离。在这里,Bracewell等人。结合联合收割机交叉实验与人口和功能基因组学的特点,新的性染色体的进化和早期物种的山松甲虫,Dendroctonus ponderosae。
Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in speciation. Here we combine extensive crossing experiments with population and functional genomic data to examine neo-XY chromosome evolution and incipient speciation in the mountain pine beetle. We find a broad continuum of intrinsic incompatibilities in hybrid males that increase in strength with geographic distance between reproductively isolated populations. This striking progression of reproductive isolation is coupled with extensive gene specialization, natural selection, and elevated genetic differentiation on both sex chromosomes. Closely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplotypes that differ in structure and male-specific gene content. Our results suggest that neo-sex chromosome evolution can drive rapid functional divergence between closely related populations irrespective of ecological drivers of divergence. The evolution of new sex chromosomes potentially generates reproductive isolation. Here, Bracewell et al. combine crossing experiments with population and functional genomics to characterize neo-sex chromosome evolution and incipient speciation in the mountain pine beetle, Dendroctonus ponderosae.
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