Protein Interaction and Na/K-ATPase-Mediated Signal Transduction.

Protein Interaction and Na/K-ATPase-Mediated Signal Transduction.
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DOI:
10.3390/molecules22060990
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发表时间:
2017-06-14
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Xie Z
Xie Z
中科院分区:
其他
文献类型:
--
作者:
Cui X;Xie Z

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The Na/K-ATPase (NKA), or Na pump, is a member of the P-type ATPase superfamily. In addition to pumping ions across cell membrane, it is engaged in assembly of multiple protein complexes in the plasma membrane. This assembly allows NKA to perform many non-pumping functions including signal transduction that are important for animal physiology and disease progression. This article will focus on the role of protein interaction in NKA-mediated signal transduction, and its potential utility as target for developing new therapeutics.
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