Bacillus velezensis FZB42 in 2018: The Gram-Positive Model Strain for Plant Growth Promotion and Biocontrol.
Bacillus velezensis FZB42 in 2018: The Gram-Positive Model Strain for Plant Growth Promotion and Biocontrol.
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DOI：
10.3389/fmicb.2018.02491
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发表时间：
2018
影响因子：
5.2
通讯作者：
Borriss R
中科院分区：
文献类型：
--
作者：
Fan B;Wang C;Song X;Ding X;Wu L;Wu H;Gao X;Borriss R
velezensis FZB42是革兰氏阳性植物生长促进和生物防治根瘤菌的模式菌株，于1998年被分离出来，并于2007年测序。为了庆祝这些周年纪念日，我们在这里总结一下关于FZB42的最新知识。近20年来，已经发表了140多篇关于FZB42的文章。起初，研究主要集中在抗菌化合物上，这些化合物显然对植物病原体具有生物防治作用，最近的研究越来越多地转向参与细菌-植物相互作用的基因的表达，调控小rna (sRNAs)，以及通过乙酰化和丙二醛化等过程修饰合成抗菌化合物的酶。迄今为止，在FZB42的基因组中已鉴定出13个参与非核糖体和核糖体合成具有抗菌作用的次级代谢物的基因簇。这些基因簇约占整个基因组的10%。抗菌化合物不仅可以抑制植物病原菌和真菌的生长，还可以刺激植物的诱导系统抗性（ISR）。研究发现，FZB42在生物（植物病原体）和非生物胁迫条件下发挥生物防治作用，除次生代谢物外，挥发性有机物也参与其中。为了方便获取基因组数据，我们建立了一个整合数据库“AmyloWiki”，其中包含了FZB42中存在的基因、可用突变株和FZB42研究的其他方面的积累信息，该数据库的结构类似于著名的SubtiWiki数据库。
Bacillus velezensis FZB42, the model strain for Gram-positive plant-growth-promoting and biocontrol rhizobacteria, has been isolated in 1998 and sequenced in 2007. In order to celebrate these anniversaries, we summarize here the recent knowledge about FZB42. In last 20 years, more than 140 articles devoted to FZB42 have been published. At first, research was mainly focused on antimicrobial compounds, apparently responsible for biocontrol effects against plant pathogens, recent research is increasingly directed to expression of genes involved in bacteria–plant interaction, regulatory small RNAs (sRNAs), and on modification of enzymes involved in synthesis of antimicrobial compounds by processes such as acetylation and malonylation. Till now, 13 gene clusters involved in non-ribosomal and ribosomal synthesis of secondary metabolites with putative antimicrobial action have been identified within the genome of FZB42. These gene clusters cover around 10% of the whole genome. Antimicrobial compounds suppress not only growth of plant pathogenic bacteria and fungi, but could also stimulate induced systemic resistance (ISR) in plants. It has been found that besides secondary metabolites also volatile organic compounds are involved in the biocontrol effect exerted by FZB42 under biotic (plant pathogens) and abiotic stress conditions. In order to facilitate easy access to the genomic data, we have established an integrating data bank ‘AmyloWiki’ containing accumulated information about the genes present in FZB42, available mutant strains, and other aspects of FZB42 research, which is structured similar as the famous SubtiWiki data bank.
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将植物营养状况与植物-微生物相互作用联系起来
影响因子：
3.7
作者：
Carvalhais LC;Dennis PG;Fan B;Fedoseyenko D;Kierul K;Becker A;von Wiren N;Borriss R
通讯作者：
Borriss R
影响因子：
3.6
作者：
Butcher, BG;Helmann, JD
通讯作者：
Helmann, JD
DOI：
10.1073/pnas.96.23.13294
发表时间：
1999-11-09
影响因子：
11.1
作者：
Duitman, EH;Hamoen, LW;Vater, J
通讯作者：
Vater, J
影响因子：
7.4
作者：
Debois, Delphine;Jourdan, Emmanuel;Ongena, Marc
通讯作者：
Ongena, Marc
影响因子：
3.5
作者：
Chowdhury, Soumitra Paul;Uhl, Jenny;Hartmann, Anton
通讯作者：
Hartmann, Anton