Roles of Children and Adolescents in COVID-19 Transmission in the Community: A Retrospective Analysis of Nationwide Data in Japan.
Roles of Children and Adolescents in COVID-19 Transmission in the Community: A Retrospective Analysis of Nationwide Data in Japan.
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DOI：
10.3389/fped.2021.705882
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发表时间：
2021
影响因子：
2.6
通讯作者：
Oshitani H
中科院分区：
文献类型：
--
作者：
Imamura T;Saito M;Ko YK;Imamura T;Otani K;Akaba H;Ninomiya K;Furuse Y;Miyahara R;Sando E;Yasuda I;Tsuchiya N;National COVID-19 Cluster Response Taskforce;Suzuki M;Oshitani H
背景：儿童和青少年在社区传播2019冠状病毒病（COVID-19）中的作用尚未完全了解。研究方法：我们利用地方政府公布的病例信息，分析了7，758名儿童和青少年COVID-19的数据以及这些病例产生的二次传播特征。计算了各种社会环境中产生二次传播的儿童和青少年病例的比率。结果如下：2020年1月15日至10月31日期间，COVID-19的发病率为每105名0至9岁人口24. 8例，10至19岁人口59. 2例，低于所有年龄组个体的发病率（每105名人口79. 6例）。在托儿所和幼儿园的婴幼儿中，继发病例的比例为8.3%，在小学的儿童和青少年中为16%，在初中的儿童和青少年中为34%，在高中的儿童和青少年中为43%，在职业培训学院的儿童和青少年中为31%，在大学的儿童和青少年中为24%。家庭是二次传播的最常见场所。结论：在患有COVID-19的儿童和青少年病例中，特别是在家庭以外的环境中，产生继发病例的风险可能有限。传统缓解措施的有效性（例如，学校关闭）以抑制COVID-19传播的措施应仔细评估。
Background: Roles of children and adolescents in spreading coronavirus disease 2019 (COVID-19) in the community is not fully understood. Methods: We analyzed the data of 7,758 children and adolescents with COVID-19 and characteristics of secondary transmission generated by these cases using case information published by local governments. Ratio of pediatric and adolescent cases generating secondary transmission was calculated for various social settings. Results: The incidence of COVID-19 was 24.8 cases per 105 population aged between 0 and 9 years, and 59.2 among those aged between 10 and 19 years, which was lower than that among individuals of all age groups (79.6 per 105 population) between January 15 and October 31, 2020. The proportion of cases generating secondary cases was 8.3% among infants and young children in nursery schools and kindergartens, 16% among children and adolescents attending primary schools, 34% among those attending junior high schools, 43% among those attending high schools, 31% among those attending professional training colleges, and 24% in those attending universities. Households were the most common setting for secondary transmission. Conclusion: The risk of generating secondary cases might be limited among pediatric and adolescent cases with COVID-19, especially in settings outside households. Effectiveness of traditional mitigation measures (e.g., school closures) to suppress COVID-19 transmissions should be carefully evaluated.
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DOI：
10.1056/nejmoa0905498
发表时间：
2009-12-31
期刊：
The New England journal of medicine
影响因子：
--
作者：
Cauchemez S;Donnelly CA;Reed C;Ghani AC;Fraser C;Kent CK;Finelli L;Ferguson NM
通讯作者：
Ferguson NM
影响因子：
19
作者：
Heavey, Laura;Casey, Geraldine;McDarby, Geraldine
通讯作者：
McDarby, Geraldine
DOI：
10.1073/pnas.1008895108
发表时间：
2011-02-15
影响因子：
11.1
作者：
Cauchemez, Simon;Bhattarai, Achuyt;Swerdlow, David
通讯作者：
Swerdlow, David
影响因子：
64.8
作者：
Cauchemez, Simon;Valleron, Alain-Jacques;Ferguson, Neil M.
通讯作者：
Ferguson, Neil M.
影响因子：
11.8
作者：
Yung, Chee Fu;Kam, Kai-qian;Ng, Kee Chong
通讯作者：
Ng, Kee Chong