All-cause and cause-specific mortality in a cohort of WTC-exposed and non-WTC-exposed firefighters.

All-cause and cause-specific mortality in a cohort of WTC-exposed and non-WTC-exposed firefighters.
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在一组WTC暴露和非WTC暴露的消防员中,全因和原因特定死亡率。

DOI:
10.1136/oemed-2022-108703
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发表时间:
2023-06
影响因子:
4.9
通讯作者:
--
中科院分区:
医学2区
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比较暴露于WTC的纽约市消防局(FDNY)消防员的死亡率与类似健康、非暴露于WTC/非FDNY消防员的死亡率,并比较每个消防员队列与一般人群的死亡率。分析包括2001年9月11日受雇的10,786名男性WTC暴露的纽约消防局消防员和8,813名来自其他城市消防部门的男性非WTC暴露消防员。只有WTC暴露的消防员通过WTC健康计划(WTCHP)接受健康监测。随访开始于2001年9月11日,结束于死亡日期或2016年12月31日(较早者)。死亡数据来自国家死亡指数,人口统计数据来自消防部门。我们估计标准化死亡率(SMR)在每个消防员队列与美国男性使用人口统计学特定的美国死亡率。Poisson回归模型估计了WTC暴露与非WTC暴露消防员的全因和特定原因死亡率的相对比率(RR),控制了年龄和种族。在2001年9月11日至2016年12月31日期间,有261名暴露于WTC的消防员死亡,605名未暴露于WTC的消防员死亡。与美国男性相比,两个队列的全因死亡率均降低(暴露于WTC和未暴露于WTC的SMR[95%CI]分别为0.30 [0.26-0.34]和0.60 [0.55-0.65])。与未接触WTC的消防员相比,接触WTC的消防员的全因死亡率(RR=0.54,95%CI=0.49-0.59)以及癌症、心血管和呼吸道疾病特定死亡率也较低。两个消防员队列的全因死亡率都低于预期。在2001年9月11日之后的15年中,暴露于WTC的消防员的死亡率低于未暴露于WTC的消防员。暴露于WTC的死亡率较低不仅表明健康工人的影响,而且还表明其他因素,例如他们通过WTCHP获得更多的免费健康监测和治疗。
To compare mortality rates in WTC-exposed Fire Department of the City of New York (FDNY) firefighters with rates in similarly healthy, non-WTC-exposed/non-FDNY firefighters, and compare mortality in each firefighter cohort with the general population. 10,786 male WTC-exposed FDNY firefighters and 8,813 male non-WTC-exposed firefighters from other urban fire departments who were employed on 9/11/2001 were included in the analyses. Only WTC-exposed firefighters received health monitoring via the WTC Health Program (WTCHP). Follow-up began 9/11/2001 and ended at the earlier of death date or 12/31/2016. Death data were obtained from the National Death Index, and demographics from the fire departments. We estimated standardized mortality ratios (SMRs) in each firefighter cohort vs. US males using demographic-specific US mortality rates. Poisson regression models estimated relative rates (RRs) of all-cause and cause-specific mortality in WTC-exposed vs. non-WTC-exposed firefighters, controlling for age and race. Between 9/11/2001-12/31/2016, there were 261 deaths among WTC-exposed firefighters and 605 among non-WTC-exposed. Both cohorts had reduced all-cause mortality compared with US males (SMR[95%CI]=0.30 [0.26-0.34] and 0.60 [0.55-0.65] in WTC-exposed and non-WTC-exposed, respectively). WTC-exposed firefighters also had lower rates of all-cause mortality (RR=0.54, 95%CI=0.49-0.59) and cancer-, cardiovascular- and respiratory disease-specific mortality compared with non-WTC-exposed firefighters. Both firefighter cohorts had lower than expected all-cause mortality. Fifteen years post-9/11/2001, mortality was lower in WTC-exposed vs. non-WTC-exposed firefighters. Lower mortality in the WTC-exposed suggests not just a healthy worker effect, but additional factors such as greater access to free health monitoring and treatment that they receive via the WTCHP.
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