Globe Axial Length Growth at Age 5 Years in the Infant Aphakia Treatment Study.
Globe Axial Length Growth at Age 5 Years in the Infant Aphakia Treatment Study.
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DOI：
10.1016/j.ophtha.2017.01.010
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发表时间：
2017-05
期刊：
影响因子：
13.7
通讯作者：
Infant Aphakia Treatment Study Group
中科院分区：
文献类型：
--
作者：
Wilson ME;Trivedi RH;Weakley DR Jr;Cotsonis GA;Lambert SR;Infant Aphakia Treatment Study Group
To report the longitudinal change in axial length from the time of unilateral cataract surgery at age 1–7 months to age 5 years, and to compare axial length growth of operated eyes to that of fellow unoperated eyes. Comparative case series Infants enrolled in Infant Aphakia Treatment Study Axial length at baseline and age 5 years and change in axial length were analyzed relative to treated versus fellow eye, visual outcome and treatment modality (contact lens versus IOL). Eyes with glaucoma or glaucoma-suspect were excluded from primary analysis but reported separately Axial length growth from preoperative to age 5 years. Seventy patients were eligible, however axial length data for both eyes were available for 64 patients at baseline and 69 patients at age 5 years. Axial length was significantly different between treated and fellow eyes, preoperatively (18.1 mm versus 18.7 mm, p <0.0001), and at the final follow-up (21.4mm versus 22.1 mm, p =0.0004). The difference in AL growth between treated and fellow eyes was not significant (3.3 mm versus 3.5 mm, p = 0.31). The change in AL in eyes was similar with both treatments (contact lens 3.2 mm and IOL 3.4 mm, P = 0.53) and did not correlate with visual outcomes (P = 0.85). Eyes receiving additional surgery to clear the visual axis opacification grew significantly more as compared to eyes not receiving surgery to clear visual axis (3.8 versus 2.7 mm, P = 0.013). Twenty glaucoma patients and 16 glaucoma-suspect patients were excluded from the above analyses. As a group, glaucoma patients showed significantly more eye growth (5.7-mm) than non-glaucoma patients (3.3-mm) and glaucoma suspect (4.3-mm). Eyes treated for monocular cataract in infancy have similar axial growth to that of fellow eyes, despite having a shorter AL at the time of surgery. The change in AL in eyes was similar with both treatments (contact lens and IOL), did not correlate with visual outcomes and was higher in eyes receiving additional surgery to clear the visual axis or eyes diagnosed with glaucoma.
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影响因子：
2.8
作者：
Griener, ED;Dahan, E;Lambert, SR
通讯作者：
Lambert, SR
影响因子：
--
作者：
Lambert, Scott R.;Buckley, Edward G.;Drews-Botsch, Carolyn;DuBois, Lindreth;Hartmann, Eugenie;Lynn, Michael J.;Plager, David A.;Wilson, M. Edward
通讯作者：
Wilson, M. Edward
影响因子：
4.4
作者：
Lambert, Scott R.;Lynn, Michael J.;Wilson, M. Edward
通讯作者：
Wilson, M. Edward
影响因子：
4.1
作者：
Flitcroft, DI;Knight-Nanan, D;O'Keefe, M
通讯作者：
O'Keefe, M
影响因子：
4.4
作者：
Trivedi, Rupal H.;Wilson, M. Edward
通讯作者：
Wilson, M. Edward