Factory quality assurance of passive radiotherapy intensity modulators for electrons using kilovoltage x-ray imaging.
Factory quality assurance of passive radiotherapy intensity modulators for electrons using kilovoltage x-ray imaging.
复制标题
使用Kilovoltage X射线成像对电子的被动放疗强度调节器的工厂质量保证。
DOI：
10.1002/acm2.13943
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发表时间：
2023-07
影响因子：
2.1
通讯作者：
Hogstrom, Kenneth R.
中科院分区：
文献类型：
--
作者：
McGuffey, Andrew S.;Pitcher, Garrett M.;Guidry, Rebecca L.;Erhart, Kevin J.;Hogstrom, Kenneth R.
这项工作开发了一种基于 X 射线的方法，用于对电子被动放射治疗强度调制器 (PRIME) 设备制造进行工厂质量保证 (QA)。该方法测量由 PRIME 设备组成的六边形网格上圆柱形岛块的位置、直径和方向的误差以及这些误差对底层强度分布的影响。 X 射线图像是通过六台 PRIME 设备获取的，这些设备针对两个岛块直径（0.158 和 0.352 cm）模拟了三种错误情况（小随机误差、大随机误差和系统误差）。每个装置中的岛块是直径恒定的 0.6 厘米长的钨圆柱体，在约 8 厘米见方的六边形网格上间隔 0.6 厘米。使用 50 kVp X 射线图像，每个岛块都会投影一条跑道，其周长适合一个函数，可以确定其位置、直径和角方向 (θ, phi)。这些测量的参数被输入到每个设备的水中（16 MeV，SSD = 103 cm）中执行的笔形束算法（PBA）剂量计算中。比较了 PBA 使用测量的和计划的（精确）岛块参数计算的强度分布。 对于每个误差情况，0.158 和 0.352 cm 设备的 θ 分布几乎相同，对于小随机、大随机和系统误差 PRIME 设备，大多数岛块的 θ 值分别在 3.2°、8.5° 和 7.5° 范围内。对于 0.158 厘米和 0.352 厘米的设备，使用测量的岛块参数和规划的岛块参数之间的相应强度差异分别在 1.0% 和 2.8%（小随机）、2.2% 和 4.8%（大随机）以及 3.2% 和 6.7%（系统）以内。这种方法通过确定计划强度分布中的错误，为制造的 PRIME 设备的工厂质量保证提供了一种可行且经济的方法，从而可以在向客户发布之前评估其质量。
This work developed an x‐ray‐based method for performing factory quality assurance (QA) of Passive Radiotherapy Intensity Modulators for Electrons (PRIME) device fabrication. This method measures errors in position, diameter, and orientation of cylindrical island blocks on a hexagonal grid that comprises PRIME devices and the impact of such errors on the underlying intensity distribution. X‐ray images were acquired of six PRIME devices, which modeled three error cases (small random, large random, and systematic errors) for two island block diameters (0.158 and 0.352 cm). Island blocks in each device, 0.6 cm long tungsten cylinders of constant diameter, were spaced 0.6 cm on a hexagonal grid over approximately 8 cm square. Using a 50 kVp x‐ray image, each island block projected a racetrack, whose perimeter was fit to a function that allowed determination of its position, diameter, and angular orientation (θ, ϕ). These measured parameters were input into a pencil beam algorithm (PBA) dose calculation performed in water (16 MeV, SSD = 103 cm) for each device. PBA calculated intensity distributions using measured and planned (exact) island block parameters were compared. Θ distributions for the 0.158 and 0.352 cm devices were nearly identical for each error case, with θ values for most island blocks being within 3.2°, 8.5°, and 7.5° for the small random, large random, and systematic error PRIME devices, respectively. Corresponding intensity differences between using measured and planned island block parameters were within 1.0% and 2.8% (small random), 2.2% and 4.8% (large random), and 3.2% and 6.7% (systematic) for the 0.158 and 0.352 cm devices, respectively. This approach provides a viable and economical method for factory QA of fabricated PRIME devices by determining errors in their planned intensity distribution from which their quality can be assessed prior to releasing to the customer.
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影响因子：
2.1
作者：
Chambers EL;Carver RL;Hogstrom KR
通讯作者：
Hogstrom KR
影响因子：
2.1
作者：
Rusk BD;Carver RL;Gibbons JP;Hogstrom KR
通讯作者：
Hogstrom KR
影响因子：
2.1
作者：
Su S;Moran K;Robar JL
通讯作者：
Robar JL
影响因子：
2.1
作者：
Hilliard EN;Carver RL;Chambers EL;Kavanaugh JA;Erhart KJ;McGuffey AS;Hogstrom KR
通讯作者：
Hogstrom KR
影响因子：
2.1
作者：
Kudchadker, R J;Antolak, J A;Hogstrom, K R
通讯作者：
Hogstrom, K R