Mapping chromatin loops in single cells.
Mapping chromatin loops in single cells.
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映射单细胞中的染色质环。
DOI:
10.1016/j.tig.2022.03.007
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发表时间:
2022-07
影响因子:
11.4
通讯作者:
Hu, Ming
中科院分区:
文献类型:
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作者:
Yu, Miao;Li, Yun;Hu, Ming
Recent advances in single cell Hi-C technologies enable the identification of cell-type-specific chromatin loops directly from complex tissues, which may help interpret non-coding GWAS variants in disease-relevant cell types. Here we briefly review the current experimental and computational strategies for mapping chromatin loops in single cells.
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