Perfluorooctanesulfonate Induces Hepatomegaly and Lipoatrophy in Mice through Phosphoenolpyruvate Carboxykinase-Mediated Glyceroneogenesis Inhibition

Perfluorooctanesulfonate Induces Hepatomegaly and Lipoatrophy in Mice through Phosphoenolpyruvate Carboxykinase-Mediated Glyceroneogenesis Inhibition
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全氟辛烷磺酸通过磷酸烯醇丙酮酸羧激酶介导的甘油新生抑制诱导小鼠肝肿大和脂肪萎缩

DOI:
10.1021/acs.estlett.0c00048
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发表时间:
2020-02
影响因子:
10.9
通讯作者:
Yong Liang
Yong Liang
中科院分区:
环境科学与生态学2区
文献类型:
--
作者:
Ling Wang;Huiming Cao;Zhen Zhou;Yu Pan;Guangliang Liu;Thanh Wang;Yawei Wang;Mingwei Xiao;Siyi Chen;Yong Liang

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全氟辛烷磺酸(PFOS)是一种持久性有机污染物,由于其毒性效应,如其对脂质代谢的潜在干扰作用,引起了人们的极大关注。接触全氟辛烷磺酸可导致小鼠肝肿大和脂肪萎缩,
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