A gene coding for an RPS2 protein is present in the mitochondrial genome of several cereals, but not in dicotyledons
A gene coding for an RPS2 protein is present in the mitochondrial genome of several cereals, but not in dicotyledons
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编码 RPS2 蛋白的基因存在于几种谷物的线粒体基因组中，但不存在于双子叶植物中
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
J. Gualberto
中科院分区：
文献类型：
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作者：
M. Vaïtilingom;M. Stupar;J. Grienenberger;J. Gualberto
摘要小麦线粒体基因组中存在一个编码与原核糖体蛋白S2同源的蛋白质的基因。小麦基因被转录成一个单一的mRNA，通过C-U转换在七个位置进行编辑，所有这些都会导致编码的氨基酸发生变化。在水稻和玉米的线粒体基因组中也存在同源基因序列，但我们未能在所有双子叶植物的线粒体DNA中确定相应的序列；在这些物种中，线粒体RPS2可能是在细胞核中编码的。与其他原核生物的RPS2序列相比，由小麦RPS2基因序列推导出的蛋白质序列具有较长的C-末端延伸。这一延伸与任何已知序列没有相似性，在玉米或水稻线粒体rps2基因中也不保守。最有可能的是，翻译后，这种多肽延伸被一种特定的多肽酶处理，产生成熟的小麦线粒体RPS2。
Abstract A gene coding for a protein that shows homologies to prokaryotic ribosomal protein S2 is present in the mitochondrial (mt) genome of wheat (Triticum aestivum). The wheat gene is transcribed as a single mRNA which is edited by C-to-U conversions at seven positions, all resulting in alteration of the encoded amino acid. Homologous gene sequences are also present in the mt genomes of rice and maize, but we failed to identify the corresponding sequences in the mtDNA of all dicotyledonous species tested; in these species the mitochondrial RPS2 is probably encoded in the nucleus. The protein sequence deduced from the wheat rps2 gene sequence has a long C-terminal extension when compared to other prokaryotic RPS2 sequences. This extension presents no similarity with any known sequence and is not conserved in the maize or rice mitochondrial rps2 gene. Most probably, after translation, this peptide extension is processed by a specific peptidase to give rise to the mature wheat mitochondrial RPS2.
影响因子：
56.9
作者：
STERN, S;POWERS, T;NOLLER, HF
通讯作者：
NOLLER, HF