The Eye of the Storm: COVID-19 Vaccination and the Eye.

The Eye of the Storm: COVID-19 Vaccination and the Eye.
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DOI:
10.1007/s40123-021-00415-5
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发表时间:
2022-03
影响因子:
3.3
通讯作者:
Agrawal R
Agrawal R
中科院分区:
医学3区
文献类型:
--
作者:
Ng XL;Betzler BK;Ng S;Chee SP;Rajamani L;Singhal A;Rousselot A;Pavesio CE;Gupta V;de Smet MD;Agrawal R

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新冠肺炎大流行以前所未有的速度激发了全球对基于新技术的新疫苗开发的反应。自广泛实施疫苗接种运动以来,出现了关于疫苗的全身副作用,包括眼部表现的病例报告。由于接种的疫苗通常不能在接受者中导致疾病,也不能诱导针对病原体的免疫反应,我们假设新冠肺炎接种后眼睛现象的发展可能是通过疫苗引发的免疫反应发生的。其中,最常见的眼部不良事件包括面神经麻痹、中心静脉窦血栓形成和急性前葡萄膜炎。这些新冠肺炎疫苗引起的眼部不良事件可能与一些新冠肺炎患者的眼部表现相似。这篇综述将全面概述已发表的可能与新冠肺炎接种相关的眼部副作用,并作为进一步研究CVIO不良事件的跳板。
The COVID-19 pandemic has galvanized the global response towards the development of new vaccines based on novel technologies at an unprecedented pace. Since the widespread implementation of vaccination campaigns, case reports on vaccines' systemic side effects, including ocular manifestations, have emerged. Since administered vaccines are generally not able to cause the disease in the recipient, or induce an immune response against the pathogen, we hypothesize that the development of ocular phenomena post-COVID-19 vaccination may occur via an immune response elicited by the vaccine. Of many, the most common ocular adverse events include facial nerve palsy, central venous sinus thrombosis and acute anterior uveitis. These COVID-19 vaccine-induced ocular (CVIO) adverse events could resemble the ocular findings in some of the COVID-19 patients. This review will provide a comprehensive overview of published ocular side effects potentially associated with COVID-19 vaccination and serve as a springboard for further research into CVIO adverse events.
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