Big bottlenecks in cardiovascular tissue engineering.

Big bottlenecks in cardiovascular tissue engineering.
复制标题

DOI:
10.1038/s42003-018-0202-8
复制
发表时间:
2018
影响因子:
5.9
通讯作者:
Wu JC
Wu JC
中科院分区:
生物学2区
文献类型:
--
作者:
Huang NF;Serpooshan V;Morris VB;Sayed N;Pardon G;Abilez OJ;Nakayama KH;Pruitt BL;Wu SM;Yoon YS;Zhang J;Wu JC

文献摘要

参考文献

被引文献

相似文献

虽然使用人类诱导的多能干细胞的组织工程是治疗心血管疾病的有前途的方法,但一些限制因素包括三维(3D)工程组织的存活、电整合、成熟度、可扩展性和免疫应答。在这里,我们讨论了组织工程领域面临的这些重要障碍,并提出了克服这些挑战的潜在方法。在这篇评论中,Ngan Huang等人讨论了心血管组织工程的最新进展以及将这些进展转化为临床的一些主要挑战。作者提出了该领域未来的研究方向。
Although tissue engineering using human-induced pluripotent stem cells is a promising approach for treatment of cardiovascular diseases, some limiting factors include the survival, electrical integration, maturity, scalability, and immune response of three-dimensional (3D) engineered tissues. Here we discuss these important roadblocks facing the tissue engineering field and suggest potential approaches to overcome these challenges. In this Comment, Ngan Huang et al. discuss recent advances in cardiovascular tissue engineering and some of the main challenges that remain in translating these advances to the clinic. The authors propose future direction for the field to focus research efforts.
DOI: 10.1038/srep45641
发表时间: 2017-04-03
期刊: Scientific reports
影响因子: 4.6
作者:
Nakane T;Masumoto H;Tinney JP;Yuan F;Kowalski WJ;Ye F;LeBlanc AJ;Sakata R;Yamashita JK;Keller BB
通讯作者: Keller BB
DOI: 10.1038/s41598-017-12048-5
发表时间: 2017-09-18
期刊: Scientific reports
影响因子: 4.6
作者:
Conant G;Ahadian S;Zhao Y;Radisic M
通讯作者: Radisic M
DOI: 10.1038/nmeth.2999
发表时间: 2014-08
期刊: NATURE METHODS
影响因子: 48
作者:
Burridge, Paul W.;Matsa, Elena;Shukla, Praveen;Lin, Ziliang C.;Churko, Jared M.;Ebert, Antje D.;Lan, Feng;Diecke, Sebastian;Huber, Bruno;Mordwinkin, Nicholas M.;Plews, Jordan R.;Abilez, Oscar J.;Cui, Bianxiao;Gold, Joseph D.;Wu, Joseph C.
通讯作者: Wu, Joseph C.
DOI: 10.1126/science.8493529
发表时间: 1993-05-14
期刊: SCIENCE
影响因子: 56.9
作者:
LANGER, R;VACANTI, JP
通讯作者: VACANTI, JP
DOI: 10.1016/j.copbio.2011.04.004
发表时间: 2011-10
影响因子: 7.7
作者:
Iyer, Rohin K.;Chiu, Loraine L. Y.;Reis, Lewis A.;Radisic, Milica
通讯作者: Radisic, Milica