Big bottlenecks in cardiovascular tissue engineering.
Big bottlenecks in cardiovascular tissue engineering.
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DOI:
10.1038/s42003-018-0202-8
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发表时间:
2018
影响因子:
5.9
通讯作者:
Wu JC
中科院分区:
文献类型:
--
作者:
Huang NF;Serpooshan V;Morris VB;Sayed N;Pardon G;Abilez OJ;Nakayama KH;Pruitt BL;Wu SM;Yoon YS;Zhang J;Wu JC
Although tissue engineering using human-induced pluripotent stem cells is a promising approach for treatment of cardiovascular diseases, some limiting factors include the survival, electrical integration, maturity, scalability, and immune response of three-dimensional (3D) engineered tissues. Here we discuss these important roadblocks facing the tissue engineering field and suggest potential approaches to overcome these challenges. In this Comment, Ngan Huang et al. discuss recent advances in cardiovascular tissue engineering and some of the main challenges that remain in translating these advances to the clinic. The authors propose future direction for the field to focus research efforts.
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影响因子:
4.6
作者:
Nakane T;Masumoto H;Tinney JP;Yuan F;Kowalski WJ;Ye F;LeBlanc AJ;Sakata R;Yamashita JK;Keller BB
通讯作者:
Keller BB
影响因子:
4.6
作者:
Conant G;Ahadian S;Zhao Y;Radisic M
通讯作者:
Radisic M
影响因子:
48
作者:
Burridge, Paul W.;Matsa, Elena;Shukla, Praveen;Lin, Ziliang C.;Churko, Jared M.;Ebert, Antje D.;Lan, Feng;Diecke, Sebastian;Huber, Bruno;Mordwinkin, Nicholas M.;Plews, Jordan R.;Abilez, Oscar J.;Cui, Bianxiao;Gold, Joseph D.;Wu, Joseph C.
通讯作者:
Wu, Joseph C.
影响因子:
56.9
作者:
LANGER, R;VACANTI, JP
通讯作者:
VACANTI, JP
影响因子:
7.7
作者:
Iyer, Rohin K.;Chiu, Loraine L. Y.;Reis, Lewis A.;Radisic, Milica
通讯作者:
Radisic, Milica