Long-Term Air Pollution and Blood Pressure in an African American Cohort: the Jackson Heart Study.

Long-Term Air Pollution and Blood Pressure in an African American Cohort: the Jackson Heart Study.
复制标题

非裔美国人队列中的长期空气污染和血压:杰克逊心脏研究。

DOI:
10.1016/j.amepre.2020.10.023
复制
发表时间:
2021-03
影响因子:
5.5
通讯作者:
Seals, Samantha R.
Seals, Samantha R.
中科院分区:
医学2区
文献类型:
--
作者:
Weaver, Anne M.;Wang, Yi;Wellenius, Gregory A.;Bidulescu, Aurelian;Sims, Mario;Vaidyanathan, Ambarish;Hickson, DeMarc A.;Shimbo, Daichi;Abdalla, Marwah;Diaz, Keith M.;Seals, Samantha R.

文献摘要

参考文献

被引文献

相似文献

非裔美国人受高血压的影响不成比例,这可能与暴露于空气污染物有关:细颗粒物(PM2.5)和臭氧(O3)。在非裔美国人杰克逊心脏研究的参与者中,我们使用对数二项回归分析在访视1(2000-2004,N= 5,191)和访视2(2005-2008,N= 4,105)时检查了1年和3年平均PM2.5和O3浓度与患病和偶发高血压之间的关联。我们使用线性回归和分层线性模型,调整了社会人口统计学、行为和临床特征,研究了收缩压(SBP)、舒张压(DBP)、脉压和平均动脉压(MAP)的相关性。分析于2017-2019年进行。我们没有观察到PM2.5或O3浓度与高血压患病率或发病率之间的相关性。在线性模型中,1年O3浓度的IQR增加与SBP升高0.67 mmHg(95% CI 0.27,1.06)、DBP升高0.42 mmHg(95% CI 0.20,0.63)和MAP升高0.50 mmHg(95% CI 0.26,0.74)相关。在分层模型中,PM2.5与SBP(-0.72,95% CI-1.31,-0.13)、DBP(-0.69,95% CI-1.02,-0.36)和MAP(-0.71,95% CI-1.08,-0.33)呈负相关。我们观察到与1年浓度和访视1的相关性减弱。我们在高血压患病率(56%)的非裔美国人人群中观察到O3与SBP、DBP和MAP之间的正相关性,以及PM2.5与SBP、DBP和MAP之间的负相关性。效应量较小,可能不具有临床相关性。
African Americans are disproportionately affected by high blood pressure, which may be associated with exposure to air pollutants: fine particulate matter (PM2.5) and ozone (O3). Among African-American Jackson Heart Study participants, we examined associations between 1-year and 3-year mean PM2.5 and O3 concentrations with prevalent and incident hypertension at visits 1 (2000-2004, N=5,191) and 2 (2005-2008, N=4,105) using log binomial regression. We examined associations with systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure, and mean arterial pressure (MAP) using linear regression and hierarchical linear models, adjusting for sociodemographic, behavioral, and clinical characteristics. Analyses were conducted 2017-2019. We did not observe associations between PM2.5 or O3 concentration and prevalent or incident hypertension. In linear models, an IQR increase in 1-year O3 concentration was associated with 0.67mmHg higher SBP (95% CI 0.27, 1.06), 0.42mmHg higher DBP (95% CI 0.20, 0.63), and 0.50mmHg higher MAP (95% CI 0.26, 0.74). In hierarchical models, PM2.5 was inversely associated with SBP (−0.72, 95% CI −1.31, −0.13), DBP (−0.69, 95% CI −1.02, −0.36) and MAP (−0.71, 95% CI −1.08, −0.33). We observed attenuated associations with 1-year concentrations and at visit 1. We observed positive associations between O3 and SBP, DBP, and MAP, and inverse associations between PM2.5 and SBP, DBP, and MAP in an African American population with high (56%) prevalence of hypertension. Effect sizes were small and may not be clinically relevant.
DOI: 10.1016/j.envres.2015.08.002
发表时间: 2015-10
影响因子: 8.3
作者:
Kingsley SL;Eliot MN;Whitsel EA;Wang Y;Coull BA;Hou L;Margolis HG;Margolis KL;Mu L;Wu WC;Johnson KC;Allison MA;Manson JE;Eaton CB;Wellenius GA
通讯作者: Wellenius GA
DOI: 10.1016/j.envres.2017.07.041
发表时间: 2017-11
影响因子: 8.3
作者:
McGuinn LA;Ward-Caviness C;Neas LM;Schneider A;Di Q;Chudnovsky A;Schwartz J;Koutrakis P;Russell AG;Garcia V;Kraus WE;Hauser ER;Cascio W;Diaz-Sanchez D;Devlin RB
通讯作者: Devlin RB
DOI: 10.1056/nejmoa1114248
发表时间: 2012-07-05
期刊: The New England journal of medicine
影响因子: --
作者:
Inker LA;Schmid CH;Tighiouart H;Eckfeldt JH;Feldman HI;Greene T;Kusek JW;Manzi J;Van Lente F;Zhang YL;Coresh J;Levey AS;CKD-EPI Investigators
通讯作者: CKD-EPI Investigators
DOI: 10.1249/mss.0b013e31827d87ec
发表时间: 2013-05
影响因子: 4.1
作者:
Bell EJ;Lutsey PL;Windham BG;Folsom AR
通讯作者: Folsom AR
DOI: 10.1161/hypertensionaha.115.06904
发表时间: 2016-07
期刊: Hypertension (Dallas, Tex. : 1979)
影响因子: --
作者:
Abdalla M;Booth JN 3rd;Seals SR;Spruill TM;Viera AJ;Diaz KM;Sims M;Muntner P;Shimbo D
通讯作者: Shimbo D