Surgical Outcomes of Robotic Resection for Sigmoid and Rectal Cancer: Analysis of 109 Patients From a Single Center in China.
Surgical Outcomes of Robotic Resection for Sigmoid and Rectal Cancer: Analysis of 109 Patients From a Single Center in China.
复制标题
机器人切除乙状结肠癌和直肠癌的手术结果：来自中国单个中心的 109 例患者的分析
DOI：
10.3389/fsurg.2021.696026
复制
发表时间：
2021
影响因子：
1.8
通讯作者：
Pan Z
中科院分区：
文献类型：
--
作者：
Peng J;Li W;Tang J;Li Y;Li X;Wu X;Lu Z;Lin J;Pan Z
背景：近年来，机器人结肠直肠手术的应用越来越广泛。其应用的安全性和可行性也已在世界范围内得到证实。然而，在中国，有限的研究提供了结肠直肠癌（CRC）患者接受机器人手术的临床数据。本研究旨在展示机器人手术的短期临床效果，并进一步证实其在中国结直肠癌患者中的安全性和可行性。方法：回顾性分析2016年6月至2019年5月中山大学肿瘤中心109例连续接受机器人手术的结直肠癌患者的临床资料。评估患者特征、肿瘤特征、治疗细节、并发症、病理细节和生存状况。结果：109例患者中乙状结肠癌35例（32.1%），直肠癌74例（67.9%）。37例（33.9%）患者接受了新辅助放化疗。乙状结肠切除术10例（9.2%），高位前切除术（HAR） 38例（34.9%），低位前切除术（LAR） 45例（41.3%），腹会阴切除术（APR） 16例（14.7%）。手术时间中位数为270分钟（120-465分钟）。所有患者病理完全切除。无术后死亡率。发生并发症11例（10.1%），其中吻合口瘘3例（2.8%），吻合口出血1例（0.9%），盆腔出血1例（0.9%），肠梗阻4例（3.7%），乳糜漏2例（1.8%），伤口延迟愈合1例（0.9%）。在中位随访17个月（1 - 37个月）时，1例（0.9%）患者发生局部复发，5例（4.6%）患者发生远处转移，1例因疾病进展死亡。结论：我们的研究结果表明，机器人手术在技术上是可行的，对于中国结直肠癌患者来说是安全的，特别是对于接受新辅助治疗的直肠癌患者。大放大镜下的机器人腹腔镜显示，在直肠系膜水肿的病例中，盆腔自主神经保留有清晰的手术空间。
Background: Robotic colorectal surgery has been increasingly performed in recent years. The safety and feasibility of its application has also been demonstrated worldwide.However, limited studies have presented clinical data for patients with colorectal cancer (CRC) receiving robotic surgery in China. The aim of this study is to present short-term clinical outcomes of robotic surgery and further confirm its safety and feasibility in Chinese CRC patients. Methods: The clinical data of 109 consecutive CRC patients who received robotic surgery at Sun Yat-sen University Cancer Center between June 2016 and May 2019 were retrospectively reviewed. Patient characteristics,tumor traits, treatment details, complications, pathological details, and survival status were evaluated. Results: Among the 109 patients, 35 (32.1%) had sigmoid cancer, and 74 (67.9%) had rectal cancer. Thirty-seven (33.9%) patients underwent neoadjuvant chemoradiotherapy. Ten (9.2%) patients underwent sigmoidectomy, 38 (34.9%) underwent high anterior resection (HAR), 45 (41.3%) underwent low anterior resection (LAR), and 16 (14.7%) underwent abdominoperineal resection (APR). The median surgical procedure time was 270 min (range 120–465 min). Pathologically complete resection was achieved in all patients. There was no postoperative mortality. Complications occurred in 11 (10.1%) patients, including 3 (2.8%) anastomotic leakage, 1 (0.9%) anastomotic bleeding, 1 (0.9%) pelvic hemorrhage, 4 (3.7%) intestinal obstruction, 2 (1.8%) chylous leakage, and 1 (0.9%) delayed wound union. At a median follow-up of 17 months (range 1–37 months), 1 (0.9%) patient developed local recurrence and 5 (4.6%) developed distant metastasis, with one death due to disease progression. Conclusions: Our results suggest that robotic surgery is technically feasible and safe for Chinese CRC patients, especially for rectal cancer patients who received neoadjuvant treatment. A robotic laparoscope with large magnification showed a clear surgical space for pelvic autonomic nerve preservation in cases of mesorectal edema.
登录
查看更多内容
影响因子：
16.2
作者：
Feng, Rui-Mei;Zong, Yi-Nan;Xu, Rui-Hua
通讯作者：
Xu, Rui-Hua
影响因子：
45.3
作者：
Jayne, David G.;Guillou, Pierre J.;Brown, Julia M.
通讯作者：
Brown, Julia M.
DOI：
10.6004/jnccn.2018.0061
发表时间：
2018-07
期刊：
Journal of the National Comprehensive Cancer Network : JNCCN
影响因子：
--
作者：
Benson AB;Venook AP;Al-Hawary MM;Cederquist L;Chen YJ;Ciombor KK;Cohen S;Cooper HS;Deming D;Engstrom PF;Grem JL;Grothey A;Hochster HS;Hoffe S;Hunt S;Kamel A;Kirilcuk N;Krishnamurthi S;Messersmith WA;Meyerhardt J;Mulcahy MF;Murphy JD;Nurkin S;Saltz L;Sharma S;Shibata D;Skibber JM;Sofocleous CT;Stoffel EM;Stotsky-Himelfarb E;Willett CG;Wuthrick E;Gregory KM;Gurski L;Freedman-Cass DA
通讯作者：
Freedman-Cass DA
影响因子：
3.9
作者：
Pai, Ajit;Marecik, Slawomir J.;Prasad, Leela M.
通讯作者：
Prasad, Leela M.
影响因子：
3.7
作者：
Kim, Jeong Yeon;Kim, Nam-Kyu;Kim, Jang Hwan
通讯作者：
Kim, Jang Hwan