Discrepancy between the survival rate and neuropsychological development in postsurgical extremely low-birth-weight infants: a retrospective study over two decades at a single institution
Discrepancy between the survival rate and neuropsychological development in postsurgical extremely low-birth-weight infants: a retrospective study over two decades at a single institution
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术后极低出生体重婴儿的存活率和神经心理发育之间的差异：单一机构二十多年的回顾性研究
DOI：
10.1007/s00383-020-04825-7
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发表时间：
2021
影响因子：
1.8
通讯作者：
Noguc
中科院分区：
文献类型：
--
作者：
Muto Mitsuru;Sugita Koshiro;Ibara Satoshi;Masuya Ryuta;Matuskubo Makoto;Kawano Takafumi;Saruwatari Yumiko;Machigashira Seiro;Sakamoto Koichi;Nakame Kazuhiko;Shinyama Shin;Torikai Motofumi;Hayashida Yoshihiro;Mukai Motoi;Ikee Takamasa;Shimono Ryuichi;Noguc
目的：坏死性小肠结肠炎（NEC）、局灶性肠穿孔（FIP）和粪相关性肠梗阻（MRI）是导致极低出生体重儿（ELBWIs）胃肠道疾病的主要疾病。我们进行了一项综述，比较了我们新生儿重症监护室中ELBWIs与这些疾病的术后结果。方法回顾性分析2001-2018年手术治疗NEC （n= 31）、FIP （n= 35）和MRI （n= 16）的elbwi病例。这一时期分为早期（2001-2005年）、中期（2006-2010年）和后期（2011-2018年）。采用Cochran-Armitage检验对数据进行分析。以asp< 0.05为统计学意义。结果合并NEC的elbwi患者生存率（早、中、晚期分别为36.4%/42.9%/61.5%,p= 0.212）和FIP （20%/50%/70.6%, p= 0.012）随时间延长而提高；所有MRI患者均存活。采用京都心理发展量表对24例患者在姿势-运动、认知-适应和语言-社会领域的神经心理发展进行评估。校正1.5岁时各领域的平均发展商为68.4（范围18-95），实足3岁时的平均发展商为69.1（范围25-108），均被认为发育不良。两组间无明显改善（p= 0.899）。结论随着生存率的提高，神经心理发育不理想。需要微创手术干预和适当的术后护理来促进进一步发展。
PurposeNecrotizing enterocolitis (NEC), focal intestinal perforation (FIP), and meconium-related ileus (MRI) are major diseases that cause gastrointestinal disorders in extremely low-birth-weight infants (ELBWIs). We conducted a review to compare the postoperative outcomes of ELBWIs with these diseases in our neonatal intensive-care unit.MethodsA retrospective chart review of ELBWIs surgically treated for NEC (n= 31), FIP (n= 35), and MRI (n= 16) in 2001–2018 was undertaken. This period was divided into early (2001–2005), middle (2006–2010), and late (2011–2018) periods. Data were analyzed with the Cochran-Armitage test. Statistical significance was defined asp< 0.05.ResultsThe survival rates in ELBWIs with NEC (early/middle/late: 36.4%/42.9%/61.5%;p= 0.212) and FIP (20%/50%/70.6%;p= 0.012) improved over time; all patients with MRI survived. The neuropsychological development of 24 cases was assessed with the Kyoto Scale of Psychological Development in the Postural-Motor, Cognitive-Adaptative, and Language-Social domains. The mean developmental quotient of all domains was 68.4 (range 18–95) at corrected 1.5 years of age and 69.1 (range 25–108) at chronological 3 years of age, both were considered as poor development. There was no improvement over time (p= 0.899).ConclusionIdeal neuropsychological development was not observed with the improvement of survival rate. Less-invasive surgical intervention and adequate postoperative care are required to encourage further development.
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极低出生体重婴儿的神经发育结果。
DOI：
--
发表时间：
2006
期刊：
--
影响因子：
--
作者：
Jihui Kang;D. C. Chung;Y. Chang
通讯作者：
Y. Chang
影响因子：
1.4
作者：
Kubota, Akio;Shiraishi, Jun;Nakayama, Masahiro
通讯作者：
Nakayama, Masahiro
酸中毒、低氧血症和低血压对极低出生体重婴儿神经发育结局的影响。
影响因子：
8
作者：
Goldstein,RF;ThompsonJr,RJ;Oehler,JM;Brazy,JE
通讯作者：
Brazy,JE
影响因子：
2.9
作者：
A. Gold;Ashley N. Danguecan;Christina Belza;Stephanie So;N. De Silva;Y. Avitzur;P. Wales
通讯作者：
P. Wales
胎便栓综合征。
影响因子：
3.8
作者：
Clatworthy Hw;Howard Wh;J. Lloyd
通讯作者：
J. Lloyd