Controlling the size of electrostatically self-assembled nanoparticles with cyclodextrin as external trigger
Controlling the size of electrostatically self-assembled nanoparticles with cyclodextrin as external trigger
复制标题
以环糊精为外部触发剂控制静电自组装纳米粒子的尺寸
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
F. Gröhn
中科院分区：
文献类型：
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作者：
Immanuel Willerich;T. Schindler;H. Ritter;F. Gröhn
该研究表明，聚电解质和有机反离子的静电自组装可以与环糊精主客体化学相结合，成为水溶液中尺寸可控的超分子纳米颗粒的新途径。纳米颗粒是由第四代聚胺胺树状大分子（PAMAM G4）作为带正电的大离子和过量带负电的阴离子重氮染料酸黄38 （Ay38）形成的，产生带负电的超分子颗粒，其流体动力学半径为30-60 nm。α-环糊精与染料的络合作用使染料的电荷密度逐渐降低，从而使染料的粒径逐渐增大，直至达到240 nm的水动力半径。动态光散射和ζ电位测量用于阐明组装尺寸和稳定性，等温滴定量热法用于确定缔合化学计量、焓和平衡常数。
This study shows how electrostatic self-assembly of polyelectrolytes and organic counterions can be combined with cyclodextrin host–guest chemistry into a novel route to size-controllable supramolecular nanoparticles in aqueous solution. Nanoparticles are formed from fourth generation polyamidoamine dendrimers (PAMAM G4) as positively charged macroions and an excess of the oppositely charged anionic diazo dye Acid Yellow 38 (Ay38), yielding negatively charged supramolecular particles with hydrodynamic radii of 30–60 nm. Stepwise complexation of the dye by α-cyclodextrin leads to a decreasing charge density and thereby caused stepwise size increase up to particles with a hydrodynamic radius of 240 nm. Dynamic light scattering and ζ-potential measurements were used to elucidate assembly size and stabilization and isothermal titration calorimetry to determine association stoichiometry, enthalpies and equilibrium constants.
在协调驱动的自组装中进行自组织。
影响因子：
18.3
作者：
Northrop, Brian H.;Zheng, Yao-Rong;Chi, Ki-Whan;Stang, Peter J.
通讯作者：
Stang, Peter J.
影响因子：
15
作者：
Meng, Huan;Xue, Min;Xia, Tian;Zhao, Yan-Li;Tamanoi, Fuyuhiko;Stoddart, J. Fraser;Zink, Jeffrey I.;Nel, Andre E.
通讯作者：
Nel, Andre E.