Noninvasive detection of macular pigments in the human eye.

Noninvasive detection of macular pigments in the human eye.
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人眼黄斑色素的无创检测。

DOI:
10.1117/1.1628240
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发表时间:
2004
影响因子:
3.5
通讯作者:
Bernstein,PaulS
Bernstein,PaulS
中科院分区:
医学3区
文献类型:
--
作者:
Gellermann,Werner;Bernstein,PaulS

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目前,人们对开发用于检测人眼中的黄斑类胡萝卜素色素的非侵入性技术有浓厚的兴趣。这些色素由叶黄素和玉米黄质组成,从饮食中摄取,被认为在预防老年性黄斑变性方面发挥重要作用,老年性黄斑变性是西方世界老年人失明的主要原因。通过适当的饮食干预策略,有可能预防或延迟这种使人衰弱的疾病的发作。我们回顾了最常用的检测技术的基础上异色闪烁光度法,眼底反射,和autofluorescense技术,并把他们的角度与最近开发的分子特异性拉曼检测方法。©2004年摄影光学仪器工程师协会。
There is currently strong interest in developing noninvasive technologies for the detection of macular carotenoid pigments in the human eye. These pigments, consisting of lutein and zeaxanthin, are taken up from the diet and are thought to play an important role in the prevention of age-related macular degeneration, the leading cause of blindness in the elderly in the Western world. It may be possible to prevent or delay the onset of this debilitating disease with suitable dietary intervention strategies. We review the most commonly used detection techniques based on heterochromatic flicker photometry, fundus reflectometry, and autofluorescense techniques and put them in perspective with recently developed more molecule-specific Raman detection methods. ©2004 Society of Photo-Optical Instrumentation Engineers.
DOI: 10.1016/0042-6989(71)90112-x
发表时间: 1971-01-01
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影响因子: 1.8
作者:
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DOI: --
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