Epidemiology of infection in pregnancy.

Epidemiology of infection in pregnancy.
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妊娠期感染的流行病学。

DOI:
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发表时间:
1985
期刊:
Reviews of Infectious Diseases
影响因子:
--
通讯作者:
B. Brabin
B. Brabin
中科院分区:
--
文献类型:
--
作者:
B. Brabin

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在这篇文章中,免疫学,临床和流行病学的证据,改变主机在怀孕期间感染的易感性进行审查,试图确定一般原则,可以适用于解释广泛的信息,可用于流行病学分析和研究设计。妊娠期免疫力的变化与母亲孕期感染史有关。原发性感染与复发性感染不同,并定义了妊娠期复发性感染的不同模式。然后,该分类系统用于解释各种数据。妊娠期感染对后代的影响与垂直传播和妊娠期免疫状态有关:妊娠期妇女感染的清除率(如果不是发病率)与非妊娠期妇女相似;母体对感染的易感性在妊娠早期改变(小于12周);母亲从妊娠早期感染中恢复的程度影响垂直传播率;关于怀孕期间感染主要热带寄生虫的模式如何与垂直传播有关的数据很少。
In this article the immunologic, clinical, and epidemiologic evidence for altered host susceptibility to infection during pregnancy is reviewed in an attempt to determine general principles that can be applied to interpret the wide range of information available and that can be utilized for epidemiologic analysis and study design. Gestational changes in immunity are related to the maternal history of infection during pregnancy. Primary infections are distinguished from recurrent infections, and the different patterns of recurrent infection in pregnancy are defined. This classification system is then used to interpret a wide range of data. The impact of infection in pregnancy on the offspring is discussed in relation to vertical transmission and pregnancy immune status: in pregnant women the clearance, if not the incidence, of infection is similar to that in nonpregnant women; maternal susceptibility to infection alters early in gestation (at less than 12 weeks); the degree of maternal recovery from early gestational infection affects vertical transmission rates; there are few data on how patterns of infection with the major tropical parasites during pregnancy relate to vertical transmission.
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DOI: 10.1093/clinids/6.1.96
发表时间: 1984
期刊: Reviews of infectious diseases
影响因子: --
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新生儿通过母亲接种疫苗进行被动免疫。
DOI: --
发表时间: 1984
影响因子: 7.2
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