An Estimation Method of Continuous Non-Invasive Arterial Blood Pressure Waveform Using Photoplethysmography: A U-Net Architecture-Based Approach.
An Estimation Method of Continuous Non-Invasive Arterial Blood Pressure Waveform Using Photoplethysmography: A U-Net Architecture-Based Approach.
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DOI：
10.3390/s21051867
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发表时间：
2021-03-07
期刊：
影响因子：
--
通讯作者：
Choi S
中科院分区：
文献类型：
--
作者：
Athaya T;Choi S
血压（BP）监测在高血压和各种心血管健康疾病的治疗中具有重要意义。由于光电体积描记图（PPG）信号可以被非侵入性地记录，因此近来已经高度地进行了使用PPG测量BP的研究。在本文中，我们提出了一种U-网络深度学习架构，该架构使用指尖PPG信号作为输入来无创地估计动脉BP（ABP）波形。根据该波形，我们还测量了收缩压（SBP）、舒张压（DBP）和平均动脉压（MAP）。所提出的方法进行了评估的一个子集的100名受试者从两个公开的数据库：MIMIC和MIMIC-III。预测的ABP波形与参考波形高度相关，我们得到了平均皮尔逊相关系数为0.993。SBP、DBP和MAP的平均绝对误差分别为3.68 ± 4.42 mmHg、1.97 ± 2.92 mmHg和2.17 ± 3.06 mmHg，符合美国医疗器械促进协会（AAMI）标准的要求，按英国高血压协会（BHS）标准评定为A级。结果表明，该方法是一个有效的过程来估计ABP波形直接使用指尖PPG。
Blood pressure (BP) monitoring has significant importance in the treatment of hypertension and different cardiovascular health diseases. As photoplethysmogram (PPG) signals can be recorded non-invasively, research has been highly conducted to measure BP using PPG recently. In this paper, we propose a U-net deep learning architecture that uses fingertip PPG signal as input to estimate arterial BP (ABP) waveform non-invasively. From this waveform, we have also measured systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP). The proposed method was evaluated on a subset of 100 subjects from two publicly available databases: MIMIC and MIMIC-III. The predicted ABP waveforms correlated highly with the reference waveforms and we have obtained an average Pearson’s correlation coefficient of 0.993. The mean absolute error is 3.68 ± 4.42 mmHg for SBP, 1.97 ± 2.92 mmHg for DBP, and 2.17 ± 3.06 mmHg for MAP which satisfy the requirements of the Association for the Advancement of Medical Instrumentation (AAMI) standard and obtain grade A according to the British Hypertension Society (BHS) standard. The results show that the proposed method is an efficient process to estimate ABP waveform directly using fingertip PPG.
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