Can Photoplethysmography Replace Arterial Blood Pressure in the Assessment of Blood Pressure?

Can Photoplethysmography Replace Arterial Blood Pressure in the Assessment of Blood Pressure?
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DOI:
10.3390/jcm7100316
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发表时间:
2018-09-30
影响因子:
3.9
通讯作者:
Elgendi M
Elgendi M
中科院分区:
医学2区
文献类型:
--
作者:
Martínez G;Howard N;Abbott D;Lim K;Ward R;Elgendi M

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动脉血压(ABP)和光体积描记(PPG)都是监测心血管状态的有用技术。虽然ABP监测得到了更广泛的应用,但这种信号采集过程无论是有创还是非有创的,都会给患者带来不便和不适。然而,PPG是一种简单、非侵入性的方法,可以用于连续测量。本文着重分析了正常血压、高血压前期和高血压患者的ABP和PPG信号在时频域上的相似性,以及考虑到分析结果对受试者进行分类的可行性。从一个有120条ABP和PPG记录的数据库中,每条记录的长度是120 S,这些记录被分成10个心跳的纪元,并进行以下统计测量:相关(R)、相干(COH)、部分相干(PCOH)、部分定向相干(PDC)、定向传递函数(DTF)、全频率定向传递函数(FFDTF)和直接定向传递函数(DDTF)。各组间的相关系数均为平均值,表明各组间形态相似性较强。对于COH和pCOH,在利用PPG信号区分正常血压和高血压受试者方面,一致性(频域线性相关)被发现具有显著意义(p<0.01)。对于手头的数据集,只有两个同步测量能够令人信服地区分高血压受试者和正常血压对照组受试者,即ffDTF和dDTF。从pdc、dtf、ffdtf和ddtf中,从总部基地→ppg中发现了一致的、强烈的显著因果关系。当所有的同步测量结合在一起时,使用神经网络分类器可以准确地检测高血压,这表明PPG拥有ABP中存在的大多数信息特征。
Arterial Blood Pressure (ABP) and photoplethysmography (PPG) are both useful techniques to monitor cardiovascular status. Though ABP monitoring is more widely employed, this procedure of signal acquisition whether done invasively or non-invasively may cause inconvenience and discomfort to the patients. PPG, however, is simple, noninvasive, and can be used for continuous measurement. This paper focuses on analyzing the similarities in time and frequency domains between ABP and PPG signals for normotensive, prehypertensive and hypertensive subjects and the feasibility of the classification of subjects considering the results of the analysis performed. From a database with 120 records of ABP and PPG, each 120 s in length, the records where separated into epochs taking into account 10 heartbeats, and the following statistical measures were performed: Correlation (r), Coherence (COH), Partial Coherence (pCOH), Partial Directed Coherence (PDC), Directed Transfer Function (DTF), Full Frequency Directed Transfer Function (ffDTF) and Direct Directed Transfer Function (dDTF). The correlation coefficient was on average for all groups, indicating a strong morphology similarity. For COH and pCOH, coherence (linear correlation in frequency domain) was found with significance (p < 0.01) in differentiating between normotensive and hypertensive subjects using PPG signals. For the dataset at hand, only two synchrony measures are able to convincingly distinguish hypertensive subjects from normotensive control subjects, i.e., ffDTF and dDTF. From PDC, DTF, ffDTF, and dDTF, a consistent, a strong significant causality from ABP→PPG was found. When all synchrony measures were combined, an accuracy was achieved to detect hypertension using a Neural Network classifier, suggesting that PPG holds most informative features that exist in ABP.
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发表时间: 2018-09-10
期刊: Diagnostics (Basel, Switzerland)
影响因子: --
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