Epstein-Barr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments.

Epstein-Barr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments.
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DOI:
10.3390/ijms232214389
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发表时间:
2022-11-19
影响因子:
5.6
通讯作者:
--
中科院分区:
生物学2区
文献类型:
--
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EB病毒(EBV)是八种已知的具有感染人类潜力的疱疹病毒之一。在全球范围内,估计90-95%的人口已感染EBV。EBV是一种致癌病毒,与各种上皮恶性肿瘤如鼻咽癌和胃癌密切相关。最近的证据表明EBV和乳腺癌之间存在联系。此外,还有其他更罕见的癌症,将它们与EBV联系起来的证据较弱。在这篇综述中,我们讨论了目前已知的与EBV相关的上皮恶性肿瘤。此外,我们还讨论并确定了与EBV相关的每种癌症最推荐的治疗和疗法。
Epstein–Barr virus (EBV) is one of eight known herpesviruses with the potential to infect humans. Globally, it is estimated that between 90–95% of the population has been infected with EBV. EBV is an oncogenic virus that has been strongly linked to various epithelial malignancies such as nasopharyngeal and gastric cancer. Recent evidence suggests a link between EBV and breast cancer. Additionally, there are other, rarer cancers with weaker evidence linking them to EBV. In this review, we discuss the currently known epithelial malignancies associated with EBV. Additionally, we discuss and establish which treatments and therapies are most recommended for each cancer associated with EBV.
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