Association between Type 2 Diabetes and Classification of Periodontal Disease Severity in Japanese Men and Women: A Cross-Sectional Study.
Association between Type 2 Diabetes and Classification of Periodontal Disease Severity in Japanese Men and Women: A Cross-Sectional Study.
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DOI：
10.3390/ijerph19138134
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发表时间：
2022-07-02
影响因子：
--
通讯作者：
Yoshinari, Nobuo
中科院分区：
文献类型：
--
作者：
Dewake, Nanae;Iwasaki, Yukiko;Taguchi, Akira;Udagawa, Nobuyuki;Yoshinari, Nobuo
关键词：
背景：以牙槽骨丢失率（ABL）和高敏c反应蛋白（hs-CRP）值为指标评价2型糖尿病与牙周病严重程度的关系。方法：对来自日本某医院的372例患者（平均年龄±SD， 53.2±11.8岁）进行横断面研究，测量所有牙齿的全景x线片和口内x线片上的ABL和牙数。结合ABL和hs-CRP将牙周病严重程度分为9组。结果：2型糖尿病48例；324人没有。单因素分析显示，2型糖尿病与年龄、性别、体重指数、牙齿数量、ABL、hs-CRP和牙周病严重程度显著相关。多变量分析显示，2型糖尿病与牙周病严重程度高的人群之间存在显著关联。在预测糖尿病存在的受试者工作特征（ROC）曲线分析中，ABL的ROC曲线下面积为0.762 (95%CI = 0.688-0.835)， hs-CRP的ROC曲线下面积为0.709 (95%CI = 0.635-0.784)，具有统计学意义。结论：本研究表明糖尿病可与牙周病严重程度分级相关，采用ABL和hs-CRP联合检测。
Background: to evaluate the association between type 2 diabetes and periodontal disease severity using the rate of alveolar bone loss (ABL) and high-sensitivity C-reactive protein (hs-CRP) value as indices. Methods: In this cross-sectional study of 372 patients (mean age ± SD, 53.2 ± 11.8 years) from a Japanese hospital, we measured ABL and number of teeth on either panoramic radiographs or intraoral dental radiographs of all teeth. Periodontal disease severity was classified into nine groups by combining ABL and hs-CRP. Results: 48 subjects had type 2 diabetes; 324 did not. Univariate analysis showed that type 2 diabetes was significantly associated with age, sex, body mass index, number of teeth, ABL, hs-CRP, and periodontal disease severity. Multivariate analysis showed significant associations between type 2 diabetes and the groups with high severity of periodontal disease. In receiver operating characteristic (ROC) curve analysis, predicting the presence of diabetes, area under the ROC curve was 0.762 (95%CI = 0.688–0.835) for ABL, and 0.709 (95%CI = 0.635–0.784) for hs-CRP, which was significant. Conclusions: this study showed that diabetes can be associated with a periodontal disease severity classification using the combination of ABL and hs-CRP.
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