The course of symptoms in the first 27 months following bereavement: A latent trajectory analysis of prolonged grief, posttraumatic stress, and depression.

The course of symptoms in the first 27 months following bereavement: A latent trajectory analysis of prolonged grief, posttraumatic stress, and depression.
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DOI:
10.1016/j.psychres.2022.114472
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发表时间:
2022-05
影响因子:
11.3
通讯作者:
Boelen, Paul A.
Boelen, Paul A.
中科院分区:
医学2区
文献类型:
--
作者:
Djelantik, A. A. A. Manik J.;Robinaugh, Donald J.;Boelen, Paul A.

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关于丧亲后最初几个月的悲伤过程,仍有很多未知之处,包括恢复轨迹的普遍性和时间、特定症状是否标志着恢复失败,以及慢性长期悲伤(PG)、创伤后应激(PTS)和抑郁症状的同时出现。在丧亲后的两年里,259 名参与者每六周完成 11 次 PG、PTS 和抑郁症问卷。我们使用潜在类别增长混合模型 (LCGMM) 来识别每种疾病具有相似轨迹的丧亲者亚组。我们使用重复测量方差分析来评估轨迹之间个体症状的差异。最后,我们调查了这三种疾病同时发生的慢性轨迹的程度。 PG 症状出现了三种轨迹:恢复性(66.4%)、慢性(25.1%)和急性恢复(8.4%)。在丧亲后 6 个月内,急性恢复组的总体严重程度和症状特征与慢性组没有区别,随后在丧亲后 6 至 18 个月期间 PG 降低。丧亲后第一年的慢性 PTS 往往与慢性 PG 和/或慢性抑郁症同时发生。 25% 的悲伤最初加剧的人在丧亲后 6 至 12 个月内恢复。这些发现强调了丧亲后最初几个月严重悲伤的临床重要性,但也表明在丧亲后第一年内诊断悲伤障碍要谨慎。
Much remains unknown about the course of grief in the early months following bereavement, including the prevalence and timing of a recovery trajectory, whether specific symptoms mark a failure to recover, and the co-occurrence of chronic prolonged grief (PG), posttraumatic stress (PTS) and depression symptoms. Two hundred fifty-nine participants completed PG, PTS and depression questionnaires up to eleven times every six weeks during the two years post-bereavement. We used Latent Class Growth Mixture Modelling (LCGMM) to identify subgroups of bereaved individuals sharing similar trajectories for each disorder. We used repeated measures ANOVA to evaluate differences in individual symptoms between trajectories. Finally, we investigated to what extent chronic trajectories of these three disorders co-occurred. Three trajectories of PG symptoms emerged: resilient (66.4%), chronic (25.1%) and acute recovery (8.4%). The overall severity and symptom profile of the acute recovery group were indistinguishable from that of the chronic group through 6 months post-bereavement, followed by reduction in PG from 6 to 18 months post-bereavement. Chronic PTS in the first-year post-bereavement tended to co-occur with chronic PG and/or chronic depression. Twenty five percent of those with initial elevations in grief recovered in the period of 6 to 12 months post-bereavement. These findings highlight the clinical importance of severe grief in the initial months following loss, but also suggests caution in diagnosing a grief disorder within the first-year post-bereavement.
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