Cognitive Outcomes After Anterior Communicating Artery Aneurysm Repair.

Cognitive Outcomes After Anterior Communicating Artery Aneurysm Repair.
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DOI:
10.1017/cjn.2018.16
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发表时间:
2018-07
期刊:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
影响因子:
--
通讯作者:
Cusimano MD
Cusimano MD
中科院分区:
其他
文献类型:
--
作者:
Nassiri F;Workewych AM;Badhiwala JH;Cusimano MD

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背景 前交通动脉(ACoA)破裂动脉瘤治疗后的长期认知和生活质量(QoL)结果尚不清楚。方法 潜在参与者均为 1992 年 7 月至 2008 年 12 月期间在同一机构接受治疗的 ACoA 动脉瘤破裂患者。所有潜在参与者均被要求填写认知失败问卷 (CFQ)、流行病学研究中心抑郁症 (CES-D) 问卷、简式 36 (SF-36) 问卷和认知状态改良电话访谈 (TICS-M)。对患者图表的基线人口统计和临床状态、术中细节和​​术后病程进行回顾性审查。认知和生活质量评估结果的报告按治疗方法(血管内线圈栓塞和翼点开颅手术或眶颅开颅手术夹闭)进行分层。结果 本研究总共纳入 82 例患者(18 例采用弹簧圈栓塞治疗,27 例采用眶颅开颅术治疗,37 例采用翼点开颅术治疗)。总共有 32 名患者(9 名接受弹簧圈栓塞治疗,11 名接受眶颅开颅手术治疗,16 名接受翼点开颅手术)完成了后续认知和生活质量问卷调查。完成问卷的患者的平均随访时间为 8.64±3.81 年。三组在评估认知状态的问卷中没有差异(TICS-M p=0.114,CFQ p=0.111)。此外,三组之间的生活质量或抑郁评分没有观察到差异。结论 在长期随访中,开放手术和弹簧圈栓塞方式下 ACoA 动脉瘤破裂患者的生活质量、认知和抑郁测试分数相似。我们的结果强调了在报告颅内动脉瘤破裂治疗后的结果时,考虑长期结果和经过验证的日常功能测量的重要性。需要更大规模的前瞻性研究来进一步探讨结果。
Background The long-term cognitive and quality-of-life (QoL) outcomes after treatment of ruptured anterior communicating artery (ACoA) aneurysms are unknown. Methods Potential participants were all consecutive patients with ruptured ACoA aneurysms who were treated at one institution from July 1992 to December 2008. All potential participants were asked to complete the Cognitive Failures Questionnaire (CFQ), Center for Epidemiology Studies-Depression (CES-D) questionnaire, Short Form 36 (SF-36) questionnaire, and Telephone Interview for Cognitive Status-Modified (TICS-M). Patient charts were retrospectively reviewed for baseline demographics and clinical status, intra-operative details, and post-operative course. Reporting of cognitive and QoL assessment results was stratified by treatment method (endovascular coil embolization and surgical clipping by pterional craniotomy or orbitocranial craniotomy). Results In total, 82 patients (18 treated with coiling, 27 by orbitocranial craniotomy, and 37 by pterional craniotomy) were included in this study. In total, 32 patients (9 treated by coiling, 11 by orbitocranial craniotomy, and 16 by pterional craniotomy) completed follow-up cognitive and QoL questionnaires. The mean follow-up for patients who completed the questionnaires was 8.64±3.81 years. The three groups did not differ in questionnaires assessing cognitive status (TICS-M p=0.114, CFQ p=0.111). Moreover, there were no observed differences in QoL or depression scores between the three groups. Conclusions At long-term follow-up, QoL, cognitive, and depression test scores of patients with ruptured ACoA aneurysms are similar across open surgery and coiling modalities. Our results emphasize the importance of considering long-term outcomes with validated daily measures of functioning when reporting on outcomes after treatment for ruptured intracranial aneurysms. Larger prospective studies are required to further explore the results.
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