PARma: identification of microRNA target sites in AGO-PAR-CLIP data.
PARma: identification of microRNA target sites in AGO-PAR-CLIP data.
复制标题
DOI:
10.1186/gb-2013-14-7-r79
复制
发表时间:
2013-07-29
期刊:
影响因子:
12.3
通讯作者:
Zimmer R
中科院分区:
文献类型:
--
作者:
Erhard F;Dölken L;Jaskiewicz L;Zimmer R
PARma is a complete data analysis software for AGO-PAR-CLIP experiments to identify target sites of microRNAs as well as the microRNA binding to these sites. It integrates specific characteristics of the experiments into a generative model. The model and a novel pattern discovery tool are iteratively applied to data to estimate seed activity probabilities, cluster confidence scores and to assign the most probable microRNA. Based on differential PAR-CLIP analysis and comparison to RIP-Chip data, we show that PARma is more accurate than existing approaches. PARma is available from http://www.bio.ifi.lmu.de/PARma
登录
查看更多内容
DOI:
10.1093/bioinformatics/btq363
发表时间:
2010-09-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Erhard F;Zimmer R
通讯作者:
Zimmer R
影响因子:
64.5
作者:
Hafner M;Landthaler M;Burger L;Khorshid M;Hausser J;Berninger P;Rothballer A;Ascano M Jr;Jungkamp AC;Munschauer M;Ulrich A;Wardle GS;Dewell S;Zavolan M;Tuschl T
通讯作者:
Tuschl T
影响因子:
14.9
作者:
Dreszer TR;Karolchik D;Zweig AS;Hinrichs AS;Raney BJ;Kuhn RM;Meyer LR;Wong M;Sloan CA;Rosenbloom KR;Roe G;Rhead B;Pohl A;Malladi VS;Li CH;Learned K;Kirkup V;Hsu F;Harte RA;Guruvadoo L;Goldman M;Giardine BM;Fujita PA;Diekhans M;Cline MS;Clawson H;Barber GP;Haussler D;James Kent W
通讯作者:
James Kent W
影响因子:
4.1
作者:
Beitzinger, Michaela;Peters, Lasse;Meister, Gunter
通讯作者:
Meister, Gunter
影响因子:
4.5
作者:
Easow, George;Teleman, Aurelio A.;Cohen, Stephen M.
通讯作者:
Cohen, Stephen M.