Mitotic moonlighting functions for membrane trafficking proteins.

Mitotic moonlighting functions for membrane trafficking proteins.
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DOI:
10.1111/j.1600-0854.2011.01184.x
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发表时间:
2011-07
期刊:
Traffic (Copenhagen, Denmark)
影响因子:
--
通讯作者:
Royle SJ
Royle SJ
中科院分区:
其他
文献类型:
--
作者:
Royle SJ

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近年来,细胞生物学家已经发现了许多以前被认为只在膜运输中起作用的蛋白质的新功能。这些被称为兼职功能的替代角色可以发生在不同的细胞内位点或细胞周期的不同阶段。在这里,我将评估有丝分裂的兼职功能的蛋白质,在间期膜运输功能的证据。其目的是确定该领域面临的关键问题,并概述今后工作的重要问题。
In recent years, cell biologists have uncovered a number of new functions for proteins that were previously thought to operate solely in membrane trafficking. These alternative roles, termed moonlighting functions, can occur at distinct intracellular sites or at different stages of the cell cycle. Here, I will evaluate the evidence for mitotic moonlighting functions of proteins that have membrane trafficking functions during interphase. The aim is to identify key issues facing the field and to outline important questions for future work.
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