A multivariate analysis of serum nutrient levels and lung function.
A multivariate analysis of serum nutrient levels and lung function.
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DOI：
10.1186/1465-9921-9-67
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发表时间：
2008-09-29
影响因子：
5.8
通讯作者：
Britton J
中科院分区：
文献类型：
--
作者：
McKeever TM;Lewis SA;Smit HA;Burney P;Cassano PA;Britton J
There is mounting evidence that estimates of intakes of a range of dietary nutrients are related to both lung function level and rate of decline, but far less evidence on the relation between lung function and objective measures of serum levels of individual nutrients. The aim of this study was to conduct a comprehensive examination of the independent associations of a wide range of serum markers of nutritional status with lung function, measured as the one-second forced expiratory volume (FEV1). Using data from the Third National Health and Nutrition Examination Survey, a US population-based cross-sectional study, we investigated the relation between 21 serum markers of potentially relevant nutrients and FEV1, with adjustment for potential confounding factors. Systematic approaches were used to guide the analysis. In a mutually adjusted model, higher serum levels of antioxidant vitamins (vitamin A, beta-cryptoxanthin, vitamin C, vitamin E), selenium, normalized calcium, chloride, and iron were independently associated with higher levels of FEV1. Higher concentrations of potassium and sodium were associated with lower FEV1. Maintaining higher serum concentrations of dietary antioxidant vitamins and selenium is potentially beneficial to lung health. In addition other novel associations found in this study merit further investigation.
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影响因子：
5
作者：
Hu, GZ;Cassano, PA
通讯作者：
Cassano, PA
DOI：
10.1164/ajrccm.155.3.9116988
发表时间：
1997-03-01
影响因子：
24.7
作者：
Chuwers, P;Barnhart, S;Balmes, JR
通讯作者：
Balmes, JR
影响因子：
9.6
作者：
Alamoudi, OSB
通讯作者：
Alamoudi, OSB
影响因子：
10
作者：
Demissie, K;Ernst, P;Joseph, L
通讯作者：
Joseph, L
影响因子：
5.4
作者：
Grievink, L;Smit, HA;Kromhout, D
通讯作者：
Kromhout, D