Risks for Gestational Diabetes Mellitus and Pregnancy-Induced Hypertension Are Increased in Polycystic Ovary Syndrome
Risks for Gestational Diabetes Mellitus and Pregnancy-Induced Hypertension Are Increased in Polycystic Ovary Syndrome
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多囊卵巢综合症患妊娠糖尿病和妊娠高血压的风险增加
DOI：
10.1155/2013/182582
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发表时间：
2013-11
影响因子：
--
通讯作者：
Yang D
中科院分区：
文献类型：
--
作者：
Wang Y;Zhao X;Zhao H;Ding H;Tan J;Chen J;Zhang R;Azziz R;Yang D
Objectives. To evaluate pregnancy outcomes and its determinants in women with polycystic ovary syndrome (PCOS). Methods. Two-hundred and twenty pregnant PCOS and 594 healthy women were followed from early pregnancy. Incidences of gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), preterm birth, twinning, and fetal growth restriction (FGR) were determined. Results. The incidence of GDM was notably higher among all PCOS combined (54.9%; OR: 2.9, 95% CI: 2.0–4.1) and PCOS subgroups, whether they conceived spontaneously (51.5%; OR: 3.3, 95% CI: 2.0–5.4), or via IVF-ET or ovarian stimulation, compared with controls (14.3%; P < 0.001). The incidence of PIH was also higher among all PCOS (10.4%; OR: 2.2, 95% CI: 1.1–4.4) and the subgroup conceiving spontaneously (11.8%; OR: 2.6, 95% CI: 1.1–6.2; P < 0.001) but not for those conceiving with IVF-ET (9.1%) or ovarian stimulation (9.4%). Lean women with PCOS (BMI <24 kg/m2) had higher incidences of GDM (51.1% versus 14.5%; OR: 5.6, 95% CI: 3.4–9.0) and PIH (8.9% versus 3.2%; OR: 3.0, 95% CI: 1.3–7.1) than lean controls. PCOS woemn with normal glucose tolerance had higher risk for PIH than their comparable control group (OR: 4.0, 95% CI: 1.3–11.7). Conclusion. This study suggested that PCOS is an independent risk factor for the development of GDM and PIH. This trial is registered with ChiCTR-RCC-11001824.
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影响因子：
3.8
作者：
Xiaomiao Zhao;Junmin Zhong;Ya-qin Mo;Xiaoli Chen;Ya-xiao Chen;Dongzi Yang
通讯作者：
Xiaomiao Zhao;Junmin Zhong;Ya-qin Mo;Xiaoli Chen;Ya-xiao Chen;Dongzi Yang
DOI：
10.1152/ajpendo.00649.2009
发表时间：
2010-04
期刊：
American journal of physiology. Endocrinology and metabolism
影响因子：
--
作者：
T. Wada;Satoko Hori-;Maine Sugiyama;E. Fujisawa;Tetsuro Nakano;H. Tsuneki;Kiyofumi Nagira;Shigeru Saito-Shigeru-S
通讯作者：
T. Wada;Satoko Hori-;Maine Sugiyama;E. Fujisawa;Tetsuro Nakano;H. Tsuneki;Kiyofumi Nagira;Shigeru Saito-Shigeru-S
影响因子：
6.1
作者：
Haakova, L;Cibula, D;Zivny, J
通讯作者：
Zivny, J
影响因子：
16.2
作者：
L. Jovanovič
通讯作者：
L. Jovanovič
影响因子：
6.1
作者：
Fauser, BCJM;Chang, J;Lobo, R
通讯作者：
Lobo, R