Endothelial cell loss after autologous rotational keratoplasty

Endothelial cell loss after autologous rotational keratoplasty
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自体旋转角膜移植术后内皮细胞损失

DOI:
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发表时间:
2004
期刊:
Graefe's Archive for Clinical and Experimental Ophthalmology
影响因子:
--
通讯作者:
R. Sundmacher
R. Sundmacher
中科院分区:
--
文献类型:
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作者:
F. Birnbaum;T. Reinhard;D. Böhringer;R. Sundmacher

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目的通过比较自体旋转穿透角膜移植术后和同种异体穿透角膜移植术后的慢性内皮细胞丢失情况,探讨免疫学因素对慢性内皮细胞丢失的影响。方法对6例自体旋转穿透角膜移植患者行指数回归分析,计算其年相对内皮细胞损失。结果自体旋转角膜移植术后内皮细胞的年相对损失率为1.1%±2.6%(平均±标准差)。对照组内皮细胞的年相对损失率为16.7%±20.8%。结论免疫因素可能是同种异体穿透性角膜移植术后慢性内皮细胞丢失的主要原因。
PurposeTo investigate whether it may be possible to ascertain the influence of immunological factors on chronic endothelial cell loss by comparing chronic endothelial cell loss after autologous rotational penetrating keratoplasty and after homologous penetrating keratoplasty.MethodsFor six patients who had undergone autologous rotational penetrating keratoplasty the relative annual loss of endothelial cells was calculated by means of an exponential regression analysis. The findings were compared with those in a homogeneous historical control group (53 patients undergoing homologous penetrating keratoplasty for keratoconus).ResultsAfter autologous rotational keratoplasty relative annual loss of endothelial cells was 1.1%±2.6% (mean ± standard deviation). Relative annual loss of endothelial cells in the control-group was 16.7%±20.8%.ConclusionsThe results of the study lead to the assumption that immunological influences might be the main cause for chronic endothelial cell loss after homologous penetrating keratoplasty.
DOI: 10.1016/s0161-6420(98)91030-2
发表时间: 1998-10-01
期刊: OPHTHALMOLOGY
影响因子: 13.7
作者:
Ing, JJ;Ing, HH;Bourne, WM
通讯作者: Bourne, WM
DOI: 10.3109/02713688509017661
发表时间: 1985-01-01
影响因子: 2
作者:
YEE, RW;MATSUDA, M;EDELHAUSER, HF
通讯作者: EDELHAUSER, HF
DOI: --
发表时间: 1995
期刊: Transactions of the American Ophthalmological Society
影响因子: --
作者:
Bourne,WM
通讯作者: Bourne,WM
DOI: 10.1016/s0002-9394(14)72898-3
发表时间: 1994-08-01
影响因子: 4.2
作者:
BOURNE, WM;HODGE, DO;NELSON, LR
通讯作者: NELSON, LR