Tomato Functional Genomics Database: a comprehensive resource and analysis package for tomato functional genomics.

Tomato Functional Genomics Database: a comprehensive resource and analysis package for tomato functional genomics.
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番茄功能基因组学数据库:番茄功能基因组学的综合资源和分析软件包。

DOI:
10.1093/nar/gkq991
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发表时间:
2011-01
影响因子:
14.9
通讯作者:
Giovannoni JJ
Giovannoni JJ
中科院分区:
生物学2区
文献类型:
--
作者:
Fei Z;Joung JG;Tang X;Zheng Y;Huang M;Lee JM;McQuinn R;Tieman DM;Alba R;Klee HJ;Giovannoni JJ

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番茄功能基因组数据库(TFGD)为存储、查询、挖掘、分析、可视化和集成大规模的番茄功能基因组数据集提供了全面的资源。通过包括代谢物图谱以及大规模番茄小RNA(SRNA)数据集,该数据库在先前描述的番茄表达数据库的基础上进行了功能扩展。已经开发了计算管道,分别处理数据库中存档的微阵列、代谢物和sRNA数据集,TFGD提供所有分析结果的下载。TFGD还旨在使用户能够通过一套有效的查询界面和分析工具轻松检索生物重要信息,包括改进的阵列探针注释以及从基因表达数据集和miRNA靶标识别共表达、显著影响的生物过程和生化途径的工具,以及整合转录本和代谢物图谱以及sRNA和mRNA序列。TFGD中的一套工具和界面允许对最近发布并不断扩展的大规模番茄功能基因组数据集进行智能数据挖掘。TFGD可在http://ted.bti.cornell.edu.上获得。
Tomato Functional Genomics Database (TFGD) provides a comprehensive resource to store, query, mine, analyze, visualize and integrate large-scale tomato functional genomics data sets. The database is functionally expanded from the previously described Tomato Expression Database by including metabolite profiles as well as large-scale tomato small RNA (sRNA) data sets. Computational pipelines have been developed to process microarray, metabolite and sRNA data sets archived in the database, respectively, and TFGD provides downloads of all the analyzed results. TFGD is also designed to enable users to easily retrieve biologically important information through a set of efficient query interfaces and analysis tools, including improved array probe annotations as well as tools to identify co-expressed genes, significantly affected biological processes and biochemical pathways from gene expression data sets and miRNA targets, and to integrate transcript and metabolite profiles, and sRNA and mRNA sequences. The suite of tools and interfaces in TFGD allow intelligent data mining of recently released and continually expanding large-scale tomato functional genomics data sets. TFGD is available at http://ted.bti.cornell.edu.
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