Calcium dynamics encode the magnitude of a graded memory underlying sensorimotor adaptation.
Calcium dynamics encode the magnitude of a graded memory underlying sensorimotor adaptation.
复制标题
钙动力学对感觉运动适应的分级记忆的大小进行编码。
DOI:
10.1152/jn.00109.2010
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发表时间:
2010
影响因子:
2.5
通讯作者:
Zakon,HaroldH
中科院分区:
文献类型:
--
作者:
Dembrow,NikolaiC;Pettit,DianaL;Zakon,HaroldH
The role of Ca2+in the induction of neural correlates of memory has frequently been described in binary terms despite the fact that many forms of memory are graded in their strength and/or persistence. We find that Ca2+dynamics encode the magnitude of sensorimotor adaptation of the electromotor output in a weakly electric fish. The neural correlate of this memory is a synaptically induced Ca2+-dependent enhancement of intrinsic excitability of neurons responsible for setting the electromotor output. Changes in Ca2+during induction accurately predict the magnitude of this graded memory over a wide range of stimuli. Thus despite operating over a range from seconds to tens of minutes, the encoding of graded memory can be mediated by a relatively simple cellular mechanism.
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影响因子:
3.5
作者:
Baroni, G;Pedrocchi, A;Pedotti, A
通讯作者:
Pedotti, A
影响因子:
1.2
作者:
Jun-nosuke Teramae;T. Fukai
通讯作者:
Jun-nosuke Teramae;T. Fukai
DOI:
--
发表时间:
2000
期刊:
The Journal of comparative neurology
影响因子:
--
作者:
G. Smith;Ying Lu;H. Zakon
通讯作者:
H. Zakon
影响因子:
2.5
作者:
Peterka, RJ;Loughlin, PJ
通讯作者:
Loughlin, PJ
影响因子:
2.5
作者:
Smith, MR;Nelson, AB;Du Lac, S
通讯作者:
Du Lac, S