Genetic Constructor: An Online DNA Design Platform.
Genetic Constructor: An Online DNA Design Platform.
复制标题
Genetic Constructor:在线 DNA 设计平台。
DOI:
10.1021/acssynbio.7b00236
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发表时间:
2017
影响因子:
4.7
通讯作者:
Bates M
中科院分区:
文献类型:
--
作者:
Bates M
Genetic Constructor is a cloud Computer Aided Design (CAD) application developed to support synthetic biologists from design intent through DNA fabrication and experiment iteration. The platform allows users to design, manage, and navigate complex DNA constructs and libraries, using a new visual language that focuses on functional parts abstracted from sequence. Features like combinatorial libraries and automated primer design allow the user to separate design from construction by focusing on functional intent, and design constraints aid iterative refinement of designs. A plugin architecture enables contributions from scientists and coders to leverage existing powerful software and connect to DNA foundries. The software is easily accessible and platform agnostic, free for academics, and available in an open-source community edition. Genetic Constructor seeks to democratize DNA design, manufacture, and access to tools and services from the synthetic biology community.
影响因子:
3.7
作者:
Bilitchenko L;Liu A;Cheung S;Weeding E;Xia B;Leguia M;Anderson JC;Densmore D
通讯作者:
Densmore D
影响因子:
3.2
作者:
Chao R;Yuan Y;Zhao H
通讯作者:
Zhao H
影响因子:
4.7
作者:
Erin H Wilson;Shiori Sagawa;James W Weis;Max G. Schubert;Mike Bissell;Brian Hawthorne;C. Reeves;Jed Dean;D. Platt
通讯作者:
D. Platt